The men lured into the van by Scarlett Johansson's character were not actors. Jonathan Glazer had hidden cameras installed in the van and only informed the men afterwards that they were in a movie.
Adam Pearson, who plays the disfigured man who is lured into the vehicle, broke his leg when he was struck by a cab on his way to audition for his role. Director Jonathan Glazer auditioned him the next day at the hospital and gave him the job.
Championship motorcycle road racer Jeremy McWilliams was cast as the motorcyclist to handle the treacherous driving conditions of the Scottish Highlands.
Jonathan Glazer did not want to use make-up for the man with neurofibromatosis. Adam Pearson was cast after the production team contacted Changing Faces, a charity supporting people with facial disfigurement. His ideas about how Scarlett Johansson's character could seduce his character were added to the script.
A paparazzi still of Scarlett Johansson, in character, falling down became a wildly popular Internet meme in which users would photoshop Johansson into various situations. As the scene was shot with hidden cameras, it was not until the movie's release that it was revealed the fall was intentional.
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