My Favorite Sitcoms from the 2000s

Aspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.

A father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.

Five friends with big egos and small brains are the proprietors of an Irish pub in Philadelphia.

Three different, but related, families face trials and tribulations in their own uniquely comedic ways.

The absurd antics of an Indiana town"s public officials as they pursue sundry projects to make their city a better place.

Level-headed son Michael Bluth takes over family affairs after his father is imprisoned. But the rest of his spoiled, dysfunctional family are making his job unbearable.

A suspended lawyer is forced to enroll in a community college with an eccentric staff and student body.

A mockumentary on a group of typical office workers, where the workday consists of ego clashes, inappropriate behavior, tedium and romance.

A gifted young teen tries to survive life with his dimwitted, dysfunctional family.

A hedonistic jingle writer"s free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.

In the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.

Liz Lemon, head writer of the sketch-comedy show "TGS with Tracy Jordan", must deal with an arrogant new boss and a crazy new star while trying to run a successful television show without losing her mind.

A mechanic, Christopher Titus, along with his brother and his friends, try to deal with his father, a lewd, crude, drinking multiple divorcee.

Yes, Dear is a comedy about two young couples and their outrageously contrasting views on parenting.

Two couples and their single friend, all at different stages in their relationships, deal with the complications of dating, commitment, and marriage.

Thirty-something Irish Catholic couple Sean and Claudia deal with their three children as well as Sean"s judgmental father and carefree brother.

Two young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.

Reba McEntire stars as the titular character in this smash sitcom about a single mom of three, navigating life in a Houston suburb.

A group of actors move to Los Angeles to make it big, but end up working as caterers.

A divorced mom tries to keep pace with everyone around her.

The Hennessy clan -- mother Cate, daughters Bridget and Kerry, and son Rory -- look to one another for guidance and support after the death of Paul, the family patriarch. Cate"s parents lend a hand.

When Holly"s father is transferred to Japan, she is sent to live with her big sister Valerie in New York City, turning Valerie"s life upside down.