Biopharma and Pharma

Microbial Testing

Spectroscopy offers rapid, accurate, and non-invasive methods for detecting and identifying microbial contaminants. Fourier-transform infrared (FTIR) spectroscopy analyzes the vibrational fingerprint of microbial cells, allowing for rapid identification of known species based on spectral libraries. Raman spectroscopy provides information about the molecular composition of microbial cells, enabling the identification of specific strains and differentiation between closely related species. 

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Browse Application Notes

Traditionally, Raman has been a technique of the material scientist, physicist or chemist, but as instrumentation continues to evolve, the power of Raman in biological and medical applications is fast being realized, not least because of the high information content provided and an excellent tolerance for water.

Identification of contaminating microbes is an important public safety issue in many fields such as the control of food quality and the manufacture of pharmaceutical and cosmetic products. Previous research has shown the potential for Raman spectroscopy in combination with chemometric methods to investigate bulk samples as well as a single bacterium and yeast cell for classification on the species and strain level.

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HORIBA Solutions

PoliSpectra® RPR for HTS

Rapid Raman Plate Reader – Multiwell Fast Raman screening

MicroRaman Spectrometer - Confocal Raman Microscope

Aqualog - A-TEEM Industrial QC/QA Analyzer

A Simple, Fast, “Column Free” Molecular Fingerprinting Technology

Simultaneous Multi-Laser Nanoparticle Tracking Analysis (NTA)

Fluorescence and Absorbance Spectrometer

Affordable Benchtop Raman Spectrometer

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Watch Webinars and Videos

A-TEEM acquires chemical ID with fluorescence spectroscopy

The webinar will be an overview of the A-TEEM technique and some specific applications for which information is gained relevant to pharmaceutical development and process analysis. Addressing such applications requires a set of tools for A-TEEM spectroscopy to help adopt the technique into labs that require Good Manufacturing Practices (GMP) and are also focused on efficiency and ease-of-use.

The need for fluorescent bioprobes has exploded in the last decades in the Life Sciences and Medical domains for applications such as bioimaging, lab-on-chip diagnostics, drug development or cell sorting.

The A-TEEM Compliance Package is now available from HORIBA and enables A-TEEM to be used in a GMP environment. Discussion points will be around both the pharmaceutical applications of A-TEEM and the details of the compliance package for GMP labs.

EzSpec Software for Duetta and its winning user experience

New camera, new imaging, new FLIM

The large variety of fluorescent probes, such as organic dyes, biological biotags and fluorescent nanostructures, are intensively studied due to their inherent suitability for a wide range of life science applications. Thanks to the complementary nature of its analytical solutions, HORIBA's unique offer covers fluorescence, particle analysis, AFM, Raman and XRF characterization techniques, helping to gain valuable insight into optical properties, size, morphology and composition of your bioprobes.

Join Dr. Kevin Dahl of Particlese LLC and Dr. Linda Kidder of HORIBA Scientific provide tips and alternative solutions for better vaccine development and quality. They will discuss the application of multi-laser nanoparticle analysis (NTA) in determining vaccine degradation and total particle count. They will also present a new analytical approach, fluorescence A-TEEM method for rapid screening of similar but different vaccine final formulations.

Quantitative imaging techniques, such as FRET-FLIM, FCS and FCCS, and RICS are powerful tools to monitor the dynamics and interactions of proteins in live cells.

Byron Purse on his work modifying Fluorescence of DNA & RNA

A-TEEM™ stands for simultaneous Absorbance, Transmission, and Fluorescence Excitation-Emission-Matrix (EEMs) Acquisition.

Automatically discover Fluorescence profiles in about 60 seconds

The simple and ideal excitation sources for TCSPC

Automatically discover Fluorescence profiles in about 60 seconds

Money down on this Head 2 Head EEM acquisition comparison

Fast auto sampling. Auto fast sampling. Auto sampling, fast

EzSpec and its apps, making research too EZ

One of those things that make EzSpec so good

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