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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9 Very Good: 8 Good: 7 Pleasant: 6
Our top picks Lowest Price First Star rating and price Top reviewed

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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features an outdoor swimming pool, shared lounge, a terrace and restaurant in Santa Cruz de la Sierra. This hotel is perfect ⭐️⭐️⭐️⭐️⭐️ It was very relaxing. The room is big and clean. King size double bed is fantastic. Guys at the reception is highly friendly 👍 The photos can't show the quality of hotel and rooms, in reality it is much better much better. Natural coffee on breakfast every day ❤️ and fresh papaya / watermelon juice for a couple of days. So highly recommend 👍

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9
Wonderful
824 reviews
Price from
$60
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Beautiful brand new hotel. Huge rooms, great breakfast ( the lady making omelettes was lovely) nice pool. Spotless

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9
Wonderful
515 reviews
Price from
$84.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Loved the Gaudi style design, the huge bed and the homemade breakfast was amazing!

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9.2
Wonderful
368 reviews
Price from
$39.60
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. the staff was exceptionally well trained, kindly and helpful

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9.1
Wonderful
354 reviews
Price from
$104.25
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Beautiful place! Really quiet and relaxing and the staff was so helpful and kind. Can't recommend this place enough and we look forward to come back!

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9.3
Wonderful
109 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. Very charming property with super friendly staff

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9.5
Exceptional
221 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. This is a gem of a hotel, decorated very tastefully around the theme of cinema. It would feel at home as an upscale boutique hotel in any major city. I only wish we had stayed longer. We enjoyed very good pizzas at its restaurant. The weather turned very cold and rainy the night we stayed so we could not walk around the neighbourhood, but it seemed very interesting to visit. Will certainly return for a longer stay next time we fly into Santa Cruz

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9.4
Wonderful
404 reviews
Price from
$97.20
per night

Hotel Cortez

Hotel in Santa Cruz de la Sierra

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available. Great hotel in the heart of SC, super clean, great facilities and staff. Breakfast is pretty good with basic options, great coffee. Beds and pillows are super comfortable. Definitely 5 star hotel. Interior design is interesting and sswimming pool area is very relaxing. Staff super attentive. Highly recommend to stay in SC.

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9
Wonderful
181 reviews
Price from
$112.50
per night

Hotel By Armonía Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz has accommodations with an outdoor swimming pool, free private parking, a... Very nice Staff, very helpful and friendly, special thanks to Daniela 🙏 Peaceful,safe and great location; whatever you need is in walking distance; Comfy swimming pool zone to rest in the evening after long hot day; Good breakfast! Awaiting to return to this lovely place

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9.1
Wonderful
58 reviews
Price from
$76.50
per night

La Siesta Hotel

Hotel in Santa Cruz de la Sierra

Featuring an outdoor pool, La Siesta Hotel offers accommodations in Santa Cruz de la Sierra. Free WiFi access is available. Each room here features cable TV and a private bathroom with free... Great location. It´s close to the commercial district. The staff is very polite and kind.

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8
Very Good
1,400 reviews
Price from
$38
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Most-booked hotels in Santa Cruz Region in the past month

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