Life's Edge
The Search for What It Means to Be Alive
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Narrated by:
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Joe Ochman
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By:
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Carl Zimmer
About this listen
“Carl Zimmer is one of the best science writers we have today.” (Rebecca Skloot, author of The Immortal Life of Henrietta Lacks)
We all assume we know what life is, but the more scientists learn about the living world - from protocells to brains, from zygotes to pandemic viruses - the harder they find it is to locate life’s edge.
Carl Zimmer investigates one of the biggest questions of all: What is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.
Life's Edge is an utterly fascinating investigation that no one but one of the most celebrated science writers of our generation could craft. Zimmer journeys through the strange experiments that have attempted to recreate life. Literally hundreds of definitions of what that should look like now exist, but none has yet emerged as an obvious winner. Lists of what living things have in common do not add up to a theory of life. It's never clear why some items on the list are essential and others not. Coronaviruses have altered the course of history, and yet many scientists maintain they are not alive. Chemists are creating droplets that can swarm, sense their environment, and multiply. Have they made life in the lab?
Whether he is handling pythons in Alabama or searching for hibernating bats in the Adirondacks, Zimmer revels in astounding examples of life at its most bizarre. He tries his own hand at evolving life in a test tube with unnerving results. Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.
Cover image Courtesy of the MRC Laboratory of Molecular Biology. © MRC Laboratory of Molecular Biology/Madeline Lancaster
©2021 Carl Zimmer (P)2021 Penguin AudioListeners also enjoyed...
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Critic reviews
“Stories that both dazzle and edify...particularly brilliant in telling the story of DNA.... Zimmer is an astute, engaging writer - inserting the atmospheric anecdote where applicable, drawing out a scientific story and bringing laboratory experiments to life. This book is not just about life, but about discovery itself. It is about error and hubris, but also about wonder and the reach of science.” (Siddhartha Mukherjee, New York Times Book Review)
“[Zimmer] embraces the question of what it means to be alive explicitly and with the enthusiasm of an accomplished and successful storyteller. Zimmer has crafted an eminently readable tale, told through the stories and personal anecdotes of the scientists who have devoted their research to defining the essence of life.” (Issues in Science and Technology)
“The pleasures of Life’s Edge derive from its willingness to sit with the ambiguities it introduces, instead of pretending to conclusively transform the senseless into the sensible.” (The Washington Post)
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Superlative
- The Biology of Extremes
- By: Matthew D. LaPlante
- Narrated by: George Newbern
- Length: 9 hrs and 27 mins
- Unabridged
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The world's largest land mammal could help us end cancer. The fastest bird is showing us how to solve a century-old engineering mystery. The oldest tree is giving us insights into climate change. The loudest whale is offering clues about the impact of solar storms. For a long time, scientists ignored superlative life forms as outliers. Increasingly, though, researchers are coming to see great value in studying plants and animals that exist on the outermost edges of the bell curve.
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Fascinating survey of amazing biology
- By Nerd's-eye view on 12-06-19
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Life's Engines
- How Microbes Made Earth Habitable
- By: Paul G. Falkowski
- Narrated by: Nick Sullivan
- Length: 7 hrs and 22 mins
- Unabridged
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Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built - and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.
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Best Science Book Ever Written. Period.
- By serine on 07-28-15
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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The Blind Watchmaker
- Why the Evidence of Evolution Reveals a Universe Without Design
- By: Richard Dawkins
- Narrated by: Richard Dawkins, Lalla Ward
- Length: 14 hrs and 40 mins
- Unabridged
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The Blind Watchmaker, knowledgably narrated by author Richard Dawkins, is as prescient and timely a book as ever. The watchmaker belongs to the 18th-century theologian William Paley, who argued that just as a watch is too complicated and functional to have sprung into existence by accident, so too must all living things, with their far greater complexity, be purposefully designed. Charles Darwin's brilliant discovery challenged the creationist arguments; but only Richard Dawkins could have written this elegant riposte.
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Challenging textbook more than an enjoyable listen
- By Eric on 01-15-12
By: Richard Dawkins
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Life’s Ratchet
- How Molecular Machines Extract Order from Chaos
- By: Peter M. Hoffman
- Narrated by: Paul Hodgson
- Length: 9 hrs and 52 mins
- Unabridged
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The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.
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For biologists to learn single molecule biophysics
- By A Synthetic Biologist on 09-04-14
By: Peter M. Hoffman
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Letters to a Young Scientist
- By: Edward O. Wilxon
- Narrated by: Joe Barrett
- Length: 4 hrs and 57 mins
- Unabridged
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Edward O. Wilson has distilled sixty years of teaching into a book for students, young and old. Reflecting on his coming-of-age in the South as a Boy Scout and a lover of ants and butterflies, Wilson threads these twenty-one letters, each richly illustrated, with autobiographical anecdotes that illuminate his career - both his successes and his failures - and his motivations for becoming a biologist.
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Long on biography, short on advice
- By A. Mandelin on 08-02-18
By: Edward O. Wilxon
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
- Unabridged
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In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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The Second Book of General Ignorance
- Everything You Think You Know Is (Still) Wrong
- By: John Lloyd, John Mitchinson
- Narrated by: Julian Elfer
- Length: 10 hrs and 46 mins
- Unabridged
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Just when you thought that it was safe to start showing off again, John Lloyd and John Mitchinson are back with another busload of mistakes and misunderstandings. Here is a new collection of simple, perfectly obvious questions you'll be quite certain you know the answers to. Whether it's history, science, sports, geography, literature, language, medicine, the classics, or common wisdom, you'll be astonished to discover that everything you thought you knew is still hopelessly wrong.
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It's all stuff from QI
- By Bonnie Kennedy on 04-07-21
By: John Lloyd, and others
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The Sediments of Time
- My Lifelong Search for the Past
- By: Meave Leakey, Samira Leakey
- Narrated by: Susan Lyons
- Length: 14 hrs and 35 mins
- Unabridged
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Preeminent paleoanthropologist Meave Leakey brings us along on her remarkable journey to reveal the diversity of our early pre-human ancestors and how past climate change drove their evolution. She offers a fresh account of our past, as recent breakthroughs have allowed new analysis of her team’s fossil findings and vastly expanded our understanding of our ancestors. Meave’s own personal story is replete with drama, from thrilling discoveries on the shores of Lake Turkana to run-ins with armed herders and every manner of wildlife, to raising her children....
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Brilliant!
- By tess koffler on 04-07-21
By: Meave Leakey, and others
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When Humans Nearly Vanished
- The Catastrophic Explosion of the Toba Volcano
- By: Donald R. Prothero
- Narrated by: Qarie Marshall
- Length: 6 hrs and 47 mins
- Unabridged
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Some 73,000 years ago, the Mount Toba supervolcano in toda's Indonesia erupted, releasing the energy of a million tons of explosives. So much ash and debris was injected into the stratosphere that it partially blocked the sun's radiation and caused global temperatures to drop for a decade. In this book, Donald R. Prothero presents the controversial argument that the Toba catastrophe nearly wiped out the human race, leaving only about a thousand to ten thousand breeding pairs of humans worldwide.
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A very special book
- By Scott Fitzsimmons on 02-02-19
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Ravenous
- Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
- By: Sam Apple
- Narrated by: Mark Bramhall
- Length: 12 hrs and 58 mins
- Unabridged
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The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
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Highly recommended, a must read.
- By Joerg on 06-10-21
By: Sam Apple
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How do neurons turn into minds? The problem of consciousness has gnawed at us for millennia. In the last century there have been massive breakthroughs that have rewritten the science of the brain, and yet the puzzles faced by the ancient Greeks are still present. In The Consciousness Instinct, the neuroscience pioneer Michael S. Gazzaniga puts the latest research in conversation with the history of human thinking about the mind, giving a big-picture view of what science has revealed about consciousness.
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Not recommended
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In Air-Borne, award-winning New York Times columnist and author Carl Zimmer leads us on an odyssey through the living atmosphere and through the history of its discovery. We travel to the tops of mountain glaciers, where Louis Pasteur caught germs from the air, and follow Amelia Earhart and Charles Lindbergh above the clouds, where they conducted groundbreaking experiments.
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Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?
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Insects might make us recoil in repugnance, but they also manufacture - or make possible in other ways - many of the things we take for granted in our daily lives. When we bite into a shiny apple, listen to the resonant notes of a violin, try on the latest fashions, receive a dental implant, or get a manicure, we are mingling with the by-products of their everyday lives.
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I Contain Multitudes
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Undoes what you've learned from the headlines
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What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.
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very interesting
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What's Gotten into You
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Every one of us contains a billion times more atoms than all the grains of sand in the earth’s deserts. If you weigh 150 pounds, you’ve got enough carbon to make 25 pounds of charcoal, enough salt to fill a saltshaker, enough chlorine to disinfect several backyard swimming pools, and enough iron to forge a 3-inch nail. But how did these elements combine to make us human?
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One of the Very Best Science Books I have Read
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What listeners say about Life's Edge
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Skeptical DoDo
- 12-25-21
Life at the Edge
This is fantastic book. I loved listening to it. It is engaging and entertaining thus keeping your attention. I learned so much from it, and I have couple science degrees. I would heartily recommend this book to anyone!
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1 person found this helpful
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- MythicalZoan
- 08-16-22
Great tour of science's quest to define life
I have read/listened to many popular books on evolution, life, consciousness etc., so ai wasn't sure if this would contain enough new material to enjoy. I was wrong.
While any of the concepts and experiments described were familiar to me, the author reports about his talks to the actual scientists themselves about these ideas. The author also switches between the historical development of ideas about life and their scientific underpinnings through out the book. I found it quite enjoyable.
There are many stories of individual scientists and their struggles and triumphs. This keeps the book from being too abstract. The descriptions of the establishment's reaction to various ideas and discoveries about life are fascinating and even insightful of the current status quo.
The concepts and thought experiments are quite engaging on their own as well.
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- tetrahymena
- 03-17-22
A thoughtful exporation on the nature of life
At one time, life seemed easy to define. As we've learned more about chemistry and biology, our once clear definitions seem to have gone the way of the dinosaur. I expected to read a book about life's origin when I started. The book went beyond those expectations. It covers the investigations of proto life in laboratories. It asks what life is through the study of viruses and looks s at the theories of viral origins. The author explores how life arose and diversified and our understanding of the lingering debates about how people have defined the beginnings of a human or an animal life.
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1 person found this helpful
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- Paul Pastusek
- 12-06-22
Looking for the initiation of life from chemistry?
About 80% of the book talks about the boundary of life and death. The terminal boundary so to speak. Interesting, but I was looking for the initial boundary of when chemical reactions become life. The last 20% explores this pretty well.
I had known about cell theory and auto catalytic reactions. But, the work on assembly theory as a defining criteria was new to me and I like the
This is an easy to understand discussion. A good start for inquiring minds, but you will have to dig deeper for a scientific explanation. I just finished the book and have not looked to see if the references are useful.
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2 people found this helpful
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- Kindle Customer
- 11-11-22
Darwin Dogma within.
Stopped reading when he spoke of Darwin evolution. It is time to move on from 17th century, pre-microscope science. So many scientists have.
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- Shelley Pospyhalla
- 06-28-23
Fascinating and well told
I’ve listened to this book several times. It is fascinating and encompasses all aspects of the material
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- Shane S Shull
- 04-29-21
What is Life?
This book explores the question of "What is life?" and how humanity has studied this idea and the many attempts at creating definitions for life throughout time.
I thought I knew a lot about the subjects discussed in this book, but I actually learned a lot of new history and science from listening to this work. Listening to this work changed some of my long held viewpoints and assumptions on what we know about the origins of life and how extremely difficult it is to even create a definition for life at our present level of scientific understanding.
I'd highly recommend this book to any rational, open minded person, who has ever wondered how much we actually know about the origins of life. There is a lot of very interesting history covered in this book as well, and will explain the state of humanity's understanding through time and how we arrived at the present.
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15 people found this helpful
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- Midwest Grandpa
- 09-01-21
Science writing for everyone, well done & fun
Great writer & great narrator. Intriguing & compelling. Most chapters are worth listening to more than once. All the stories & details are woven together nicely & realistically by the end of the book. I highly recommend it.
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3 people found this helpful
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- Beth Purkhiser
- 09-06-21
What is life?
This is the question you will ask yourself after reading this book. Zimmer gives us just enough information to allow us to formulate our own understanding of life. Thought-provoking!
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- Tom
- 03-26-22
Wide-ranging tour of Life’s Biology
Enjoyable and educational, as Zimmer introduces the reader to so many figures significant in the centuries long search for understanding of the nature of Life and its origins. The book’s emphasis was heavier on the biology rather than the philosophical debates surrounding this issue than I would have liked but satisfying nonetheless.
Four Stars. ****
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2 people found this helpful