Sara Holland

Sara Holland

Nottingham, England, United Kingdom
8K followers 500 connections

About

Being in love with synbio, I support a number of early stage scientist-founded synthetic…

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Experience

  • Potter Clarkson Graphic

    Potter Clarkson

    Nottingham, England, United Kingdom

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    Nottingham, England, United Kingdom

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    Nottingham, United Kingdom

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Education

  • University of Nottingham Graphic

    University of Nottingham

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    Generation and modification, using phage integrases not previously used in S. pombe, a minichromosome with the aim to alter regions of the fission yeast centromere and further elucidate aspects of centromere function. Used Dam-ID to obtain structural information about the fission yeast centromere and binding regions of the centromeric protein Cenp-C, and compared the use of the technique to the more commonly used ChIP.

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Publications

  • Heterogeneous expression of the virulence-related adhesin Epa1 between individual cells and strains of the pathogen Candida glabrata

    Halliwell SC, Smith MCA, Muston P, Holland SL, Avery SV

  • The essential iron-sulfur protein rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species.

    Molecular Biology of the Cell

    Alhebshi A, Sideri TC, Holland SL, Avery SV

  • Candida argentea sp. nov., a copper and silver resistant yeast species

    Holland SL, Dyer PS, Bond CJ, James SA, Roberts IN, Avery SV

  • Chromate toxicity and the role of sulfur

    Holland SL and Avery SV

  • Chromate-induced sulfur starvation and mRNA mistranslation are linked in a common mechanism of Cr toxicity

    Holland SL, Ghosh E, Avery SV

  • Actin mediated endocytosis limits intracellular Cr accumulation and Cr toxicity during chromate stress

    Holland SL and Avery SV

  • Application of the comprehensive set of heterozygous deletion mutants to elucidate the molecular basis of chromium toxicity

    Holland S, Lodwig E, Sideri T, Reader T, Clarke I, Gkargkas K, Hoyle DC, Delneri D, Oliver SG, Avery SV

  • Comparison of Dam tagging and chromatin immunoprecipitation as tools for identification of the binding site for S. pombe CENP-C

    Holland S, Ioannou D, Haines S, Brown WRA

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