HydRegen

👀 Our Non-Exec Director, Joe de Sousa and our CEO, Holly Reeve discussing '3 things they like about working together', on camera 🎥 🚀 Introducing our ambition for delivering next-generation bio-manufacturing technologies into the Pharmaceutical sector ⏭️ Next-time we get more technical on #sustainability and our #Bio2Amine technology - watch this space 🙏 Special thanks to Tara Lurshay for filming, editing and keeping us on topic! #CPHIMilan #AtTheHeartOfPharma Meet us at CPHI Milan, in the start-up market See our website for more: https://lnkd.in/epuYN9Ym

As we transition to a more bio-based chemicals sector, are there unintended negative consequences, and can these be mitigated? Using biocatalysis and bio-based manufacturing as a cornerstone for a sustainable chemical industry has gained traction. Benefits range from: 👉 a finite to renewable catalyst switch, 👉 mild operating conditions, and 👉 exquisite chemical selectivity. However, for some chemical processes, biocatalysts require chemical energy, often provided in the form of sugar (glucose). Since glucose is derived from renewable biomass, this might still seem a good alternative to high-energy chemical manufacturing strategies, but are there unintended consequences, and what can we do about them? For example, transitioning the chemicals sector to fully bio-based feedstocks at scale would put huge pressure on our agriculture system, and generate large quantities of waste. At HydRegen, we believe there are benefits to both intensive, efficient traditional chemistry strategies, as well as in next-generation bio-manufacturing methods. We bring together the benefits and expertise of both fields. At our core, we use 💯% atom efficient Hydrogen gas from chemistry, as a replacement for 1️⃣ % atom efficient glucose used by many bio-manufacturing strategies. This results in a clean and efficient ‘slot in’ biomanufacturing solution. This brings live cost and sustainability improvements, and is part of the solution to mitigating other unintended consequences of bio-manufacturing. 🔗 Read more on our website: https://lnkd.in/eFxJ6XRw 📽️ Watch the video with Joe de Sousa and Holly Reeve: https://lnkd.in/eqK_JZKD ✉️ [email protected]

"There is an appetite for new technologies in chemical manufacturing" and "the time is right" in terms of sustainability, regulatory and societal needs - Joe de Sousa. As society becomes more carbon conscious, swapping to sustainable alternatives can be daunting - the HydRegen catalyst technologies not only provide the sustainability gains but are an easy-to-adopt ‘slot-in’ alternative for current infrastructure. Using our catalysts helps to reinforce supply chain robustness and simplify downstream-processing by moving away from precious metals, plus turning down the temperature & pressure offers improved operational safety, energy-savings and increased process profitability. Hear our NED Joe de Sousa, and CEO Holly Reeve discussing just this, why now is the time to start the switch and how HydRegen is positioned to make this switch as easy as possible.

What a great event, we enjoyed every minute at CPHI #CPHIMilan. It was great to be part of the start-up market, firstly to share ideas and experiences with the other start-ups, but also because the 'market' attracted visitors that are particularly excited about innovation and new opportunities. We were delighted that people 'got' what we are doing, really quickly, and that our messages are inline with next-generation API manufacturing needs and wish lists. Currently enjoying following up with people we met, setting up calls, and diving deeper into what our technologies can do. #Bio2Amine #Innovation #Startup #AtTheHeartOfPharma Holly Reeve, Matthew Hodges, Ph.D, Sarah Cleary, PhD and Tara Lurshay walked something like 90km around the event space!

🧩 𝗧𝗼𝗽 𝟰 𝗥𝗲𝗮𝘀𝗼𝗻𝘀 𝗪𝗵𝘆 𝗦𝗹𝗼𝘁-𝗜𝗻 Bio-manufacturing 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝗶𝗲𝘀 𝗔𝗿𝗲 𝗘𝘀𝘀𝗲𝗻𝘁𝗶𝗮𝗹 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗙𝘂𝘁𝘂𝗿𝗲 𝗼𝗳 𝗖𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗠𝗮𝗻𝘂𝗳𝗮𝗰𝘁𝘂𝗿𝗶𝗻𝗴    Slot-in technologies are innovations that can be integrated into existing chemical manufacturing processes and infrastructure with minimal disruption. They are designed to work alongside current systems, enhancing performance without requiring a complete overhaul.  By levering existing equipment and plant infrastructure, chemical manufacturing companies can maintain a competitive advantage whilst shifting to new sustainable processes that improve energy efficiencies and reduce waste: 𝟭. 𝗦𝗲𝗮𝗺𝗹𝗲𝘀𝘀 𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗘𝘅𝗶𝘀𝘁𝗶𝗻𝗴 𝗦𝘆𝘀𝘁𝗲𝗺𝘀 🔧  By using existing equipment and infrastructure, companies can avoid significant capital investments while still achieving enhanced performance. 𝟮. 𝗖𝗼𝗻𝘁𝗶𝗻𝘂𝗼𝘂𝘀 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗺𝗲𝗻𝘁𝘀 𝗳𝗼𝗿 𝗜𝗺𝗽𝗿𝗼𝘃𝗲𝗺𝗲𝗻𝘁 📈  Slot-in technologies deliver steady, measurable improvements in efficiency, yield, and environmental impact, with manageable adoption process, contributing to long-term operational gains. 𝟯. 𝗖𝗼𝘀𝘁-𝗘𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 𝗜𝗻𝘃𝗲𝘀𝘁𝗺𝗲𝗻𝘁 💡  With lower upfront capital requirements due to minimal infrastructure changes, slot-in technologies offer an attractive return on investment. The shorter payback period further strengthens their appeal, and lowers risk of adoption. 𝟰. 𝗔𝗱𝗮𝗽𝘁𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗔𝗰𝗿𝗼𝘀𝘀 𝗣𝗿𝗼𝗰𝗲𝘀𝘀𝗲s 🔄  Broad scope platform technologies are versatile and capable of accommodating various feedstocks and product lines without requiring significant reconfiguration. This flexibility allows companies to explore new materials or processes, reducing risk while maintaining operational continuity. Slot-in technologies can provide a practical and efficient pathway for chemical manufacturers to optimise performance, enhance sustainability, and remain agile in a rapidly evolving market. The ability to deliver improvements with minimal disruption positions them as a critical tool in the modern manufacturing landscape. 𝗛𝘆𝗱𝗥𝗲𝗴𝗲𝗻 𝗦𝗹𝗼𝘁-𝗜𝗻 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝗶𝗲𝘀 At HydRegen, our pioneering biomanufacturing solutions bring together the best of biology and chemistry for cleaner, safer, cheaper chemical production and more importantly, our technology has been designed from the outset to utilise or ‘slot-in’ to existing chemical manufacturing infrastructure. Lowering barriers to entry and supporting the chemical industry to become more sustainable whilst maintaining cost and operational efficiencies. 𝗖𝘂𝗿𝗶𝗼𝘂𝘀 𝘁𝗼 𝗹𝗲𝗮𝗿𝗻 𝗺𝗼𝗿𝗲 - https://lnkd.in/eNnr5VeV   𝗦𝘁𝗮𝗿𝘁 𝗮 𝗰𝗼𝗻𝘃𝗲𝗿𝘀𝗮𝘁𝗶𝗼𝗻 - [email protected]  #biotechnology #greenchemistry #Biomanufacturing #Bio2Amine #biocatalyst  #engineeringbiology  

⏭️ 𝗕𝗶𝗼𝗹𝗼𝗴𝘆 𝗳𝗼𝗿 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆: 𝗧𝗵𝗲 𝗘𝗮𝘀𝘆 𝗦𝗵𝗶𝗳𝘁 𝘄𝗶𝘁𝗵 𝗛𝘆𝗱𝗥𝗲𝗴𝗲𝗻 At HydRegen, we believe it’s time for a change.  Chemical manufacturing is an industry that impacts almost every aspect of our lives, but it needs to address sustainability challenges, reduce costs and become safer. While biotechnology holds promise, current solutions face barriers to widespread adoption. 𝗧𝗵𝗲 𝗖𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀: • Low Productivity  • Need for New Infrastructure  • Waste Generation  • High Carbon Footprint    𝗧𝗵𝗲 𝗛𝘆𝗱𝗥𝗲𝗴𝗲𝗻 𝗔𝗱𝘃𝗮𝗻𝘁𝗮𝗴𝗲: 🔹Seamless Integration: We make it simple to adopt our technology within existing systems—no need for costly new plants or complex overhauls. 🔹 Major CO2e Reductions: Achieve up to 3x CO2e savings compared to traditional metal catalysts, thanks to lower energy demands, metal replacement, and the option for continuous processing. 🔹 Cost-Effective Solutions: Aligning cost and carbon savings, our approach offers up to 40% cost reductions and minimises the need for Capex investments. 🔹 Proven Commercial Flexibility: We use strategies aligned with established processes, ensuring a smooth transition to sustainable practices. 🔹 Simplified IP Requirements: With HydRegen, there’s no need for new intellectual property or engineering of specific enzymes. At HydRegen, we’re making the switch to sustainable chemistry easy. Helping the chemical industry move towards a cleaner, safer and more efficient future. 💡 Find out more: https://lnkd.in/eNnr5VeV #Sustainability #Biotechnology #HydRegen #BioChemistry #FutureOfChemistry #GreenChemistry

Day 1 CPHI Milan - wonderful to make positive connections with brilliant, innovatove and future thinking companies like FABRX Cannovation Clinical Research Partners Pharmly Metinor Xerimis TENACO LABS PharmaTrace Centre de production de produits biologiques (CPPB) inc. / Biologics Manufacturing Centre (BMC) Inc. Butterfly Decisions AllocNow myotwin Revolve Healthcare oloBion | OMICS Life Lab NOVECAL HydRegen PluumoPlus NADMED Ltd. Brio Pharmaceuticals Inc Hypha Discovery Ltd Savendor Brenta S.r.l. Vector and Upperton Pharma Solutions ♥️ #CPHI #Milan #Connections #Clinical #Pharma #HealthCare #Industry #Logistics #Coldchain #heart #innovation #digital

💡 𝗛𝘆𝗱𝗿𝗼𝗴𝗲𝗻𝗮𝘁𝗶𝗼𝗻 𝘀𝗶𝗺𝗽𝗹𝗶𝗳𝗶𝗲𝗱    Next up in our simplified science series is a specific kind of catalysis called hydrogenation and you guessed it, it relies on hydrogen atoms! Hydrogenation is a chemical reaction between hydrogen gas and an organic compound or element, typically in the presence of a catalyst (catalysis). These catalysts, often nickel, palladium or platinum increase the reaction rate without being consumed in the process.   When hydrogen is introduced to molecules with double or triple bonds (unsaturated molecules) the unsaturated bonds become saturated single bonds, turning an unsaturated hydrocarbon into a less-saturated one. Used widely across many industries, from food to petro, pharma and polymers, hydrogenation is an essential process, but many of these processes rely on expensive, rare, toxic, and precious metal catalysts like palladium and platinum.  So, as the chemical industry looks to become more sustainable, the challenge is to find plentiful alternatives that are cheap to use and safe to handle.    🌿 One option is to use bio-based catalysts    These have the benefit of being natural and thus safe to handle. Combined with higher precision, bio-based catalysts formulated with enzymes can help improve process efficiencies and lower energy requirements, reducing environmental impact and costs. ✅ Resulting in a more sustainable chemical industry    Curious to learn more - https://lnkd.in/eNnr5VeV  Start a conversation - [email protected] #Hydrogenation #Bio2Amine #biotechnology #enzymes 

Day 2 at #CPHIMilan!

From a PhD in the US, to a start-up in the UK... Following the introduction of Yinqi and her expertise in biocatalysis, we now turn to synthetic organic chemist, Rebecca Bogart. Becky’s decision to join HydRegen was motivated by her interest in being part of a startup’s dynamic and fast-paced environment. Attracted by the potential to take on diverse responsibilities to broaden her skill set and gain experience, she was also excited by the opportunity to witness and contribute to the company's growth. A decision that prompted her move from academia in the United States to the UK. Read more: https://lnkd.in/efxmCPH7 #GreenChemsitry #Diversity #ProfessionalDevelopment #Startup #Bio2Amine #Growth #Interdisciplinary