Don’t miss Richard J. Law, our Chief Business Officer, presenting at the Automated Synthesis Forum next week! Rich will give an overview on the role of AI, automation and partnerships in drug discovery at Exscientia. Learn more about the event here: https://lnkd.in/e8aGrnHz #AI #Automation #DrugDiscovery
Exscientia
Biotechnology Research
Oxford, Oxfordshire 49,097 followers
Better drugs, faster
About us
Exscientia is a global pharmatech company using patient-first artificial intelligence (AI) to discover better drugs, faster. Our mission is to encode, automate and transform every stage of the drug design and development process, by combining the latest AI techniques with experimental innovation, to enable the design of patient centric drug candidates with an improved probability of success. Our validated platform has delivered the first three AI-designed drugs to enter clinical trials and is the first AI system proven to improve clinical outcomes in oncology. We’ve significantly accelerated pre-clinical drug discovery, with 10x productivity improvement in delivering a drug candidate compared with industry standards. By actively applying AI to precision engineer medicines more rapidly and efficiently, we allow the best ideas of science to rapidly become the best medicines for patients.
- Website
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https://www.exscientia.com
External link for Exscientia
- Industry
- Biotechnology Research
- Company size
- 201-500 employees
- Headquarters
- Oxford, Oxfordshire
- Type
- Public Company
- Founded
- 2012
- Specialties
- Artificial Intelligence, AI Drug Discovery, Tech Enabled Drug Development, Precision Medicine, Pharmaceuticals, and Technology
Locations
Employees at Exscientia
Updates
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If you’re attending Bio-Europe 2024 today, make sure you catch Nikolaus Krall, Exscientia’s EVP of Precision Medicine on the AI panel. Nikolaus will be discussing how AI algorithms are reshaping our landscape, accelerating the identification and development of novel therapeutics, in the session titled ‘I Have a Dream - AI for drug discovery’. Find out more here https://lnkd.in/dnuNZ2D #AI #AIDrugDiscovery
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Happy Sustainability Day! At Exscientia, we're committed to minimising our environmental impact and leading the way in sustainable innovation. Our state-of-the-art automation studio embodies this commitment and has been designed with this in mind: - Powered by 100% renewable electricity: We're harnessing the power of nature to fuel our research - Smart LED lighting: Efficiently illuminating our workspaces while reducing energy consumption - High-efficiency air source heat pumps: Optimising our energy use across all seasons These measures not only reduce our carbon footprint, but also demonstrate our dedication to sustainable science. We're excited to continue evolving and innovating towards a greener future for drug discovery.
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At Exscientia, our research is inspired by the millions of people and their loved ones affected by breast cancer. Our scientists are dedicated to pushing the boundaries of innovation, including with our investigational CDK7 inhibitor, using AI to explore potential new therapies that could change the lives of people living with breast cancer. We believe that every breakthrough brings us closer to more personalised, effective treatments. This October, in recognition of Breast Cancer Awareness Month, we stand with the people affected by breast cancer and reaffirm our commitment to transforming the future of cancer care. #Exscientia #BreastCancerAwarenessMonth #InnovationInHealth #AIForGood #BreastCancerResearch
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Check out Erin Aho's poster at ENA today, (Cat #414, Poster board 402) to learn more about Xcellomics, which brings together research excellence and industrial expertise to accelerate the translation of functional genomic or compound screening data into drug candidates that have the highest chances of addressing unmet clinical need. To find out more, visit the Xcellomics website: https://lnkd.in/g9gPgGsS #ENASymp24 #drugdiscovery #oncology
I am excited to present a poster entitled “Powering Rapid Translation of HTS Outputs to AI-driven Drug Discovery Programmes” at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. Xcellomics is a collaboration between Exscientia and the University of Oxford with the mission to accelerate the translation of novel biological discoveries into cancer drug candidates. Our poster highlights an example screen showing the process used to rapidly transition from functional genomic screens to therapeutic target ID and validation, then automated chemical hit ID. If you are attending, please stop by PB 402! #ENASymp24
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Don’t miss Rin Okumura presenting our poster at ENA today, (Cat #250, Poster board 238) showcasing the latest preclinical data for our highly differentiated LSD1 inhibitor EXS74539. The poster details the identification of PD biomarkers related to ‘539 treatment, as well as ‘539 efficacy in a preclinical AML model with limited impact on platelet levels. For anyone not at ENA, you can download the poster from our website: https://bit.ly/ENA_LSD1 #ENASymp24 #drugdiscovery #oncology
I’m delighted to present our latest LSD1 inhibitor preclinical data at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics today. Our poster highlights how combining human primary samples as a disease-relevant model system with drug perturbation experiments (transcriptomics, high-content imaging) can help identify novel PD biomarkers. Integrating multiple data levels with matched ex vivo sensitivity to '539 enhances the translational significance of these biomarkers, while preserving and understanding inter-patient variability in response to treatment with '539. In vivo experiments confirmed the upregulation of the biomarker candidates in response to '539 treatment, supporting the concept of introducing relevant model systems early in drug discovery to help provide clinically relevant preclinical data. If you’re attending ENA 2024, feel free to reach out or stop by PB238. #ENASymp24
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We’re delighted to announce that we’ve achieved milestones for two programmes in our Sanofi collaboration. Both programmes have demonstrated our ability to design highly differentiated molecules, which have the potential to produce best-in-class assets. We will receive an aggregate of $15 million for achieving these milestones and are eligible for over $600 million in additional milestone payments for the two programmes, as well as high-single-digit to mid-teen royalties. Learn more here: https://lnkd.in/ejya2zqW
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Interesting article from Genetic Engineering & Biotechnology News on AI in Drug Design, including thoughts from Thorsten Nowak, Exscientia’s VP of Medicinal Chemistry. Thorsten discusses how coupling predictive modelling and AI-driven design with automated experimentation, alongside a multiparametric approach to drug design, allows Exscientia to secure optimised solutions to problems and find potentially better drugs, more efficiently: https://lnkd.in/gKuQhEaz #AI #drugdesign #automation #medicinalchemistry
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We’re excited to announce that we’ll be presenting new preclinical data for both our LSD1 and MALT1 inhibitor programmes at the upcoming ENA Symposium in October 2024. Learn more here: https://lnkd.in/eXv7Khw4 Our posters highlight: - The combination potential for MALT1 and BTK inhibitors in models of B-cell malignancies - The efficacy of EXS74539 in a preclinical AML model, with limited impact on platelet levels, and the identification of PD biomarkers related to LSD1 inhibitor treatment #ENASymp24 #drugdiscovery #oncology
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