8-Dimetilalilnaringenin 2'-hidroksilaza
| 8-Dimetilalilnaringenin 2'-hidroksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.103 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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8-Dimetilalilnaringenin 2'-hidroksilaza (EC 1.14.13.103, 8-DMAN 2'-hidroksilaza) je enzim sa sistematskim imenom soforaflavanon-B,NADPH:kiseonik oksidoreduktaza (2'-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- soforaflavanon B NADPH H O2 leahianon G NADP H2O
Ovaj za membranu vezani hem-tiolatni protein je asociran sa endoplazmičnim retikulumom. On je specifičan za soforaflavanon B kao supstrat. NADPH se ne može zameniti drugim kofaktorima.
Reference
[уреди | уреди извор]- ^ Yamamoto, H., Yatou, A. and Inoue, K. (2001). „8-Dimethylallylnaringenin 2′-hydroxylase, the crucial cytochrome P450 mono-oxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells”. Phytochemistry. 58: 671—676. PMID 11672730.
- ^ Zhao, P., Inoue, K., Kouno, I. and Yamamoto, H. (2003). „Characterization of leachianone G 2′′-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures”. Plant Physiol. 133: 1306—1313. PMID 14551337.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 8-dimethylallylnaringenin 2'-hydroxylase на US National Library of Medicine Medical Subject Headings (MeSH)
