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Sulfamazon

Izvor: Wikipedija

Sulfamazon

Klinički podaci

AHFS/Drugs.com

Identifikatori

PubChem^[1]^[2]

KEGG^[3]

Hemijski podaci

C₂₃H₂₄N₆O₇S₂

560,603

eMolekuli & PubHem

InChI
InChI=1S/C23H24N6O7S2/c1-15-21(23(30)29(28(15)2)17-7-5-4-6-8-17)22(38(33,34)35)24-16-9-11-18(12-10-16)37(31,32)27-19-13-14-20(36-3)26-25-19/h4-14,22,24H,1-3H3,(H,25,27)(H,33,34,35) Key: BGLHAKAJGYLSOX-UHFFFAOYSA-N^Y

Farmakoinformacioni podaci

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Sulfamazon je organsko jedinjenje, koje sadrži 23 atoma ugljenika i ima molekulsku masu od 560,603 Da.

Osobine

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Osobina	Vrednost
Broj akceptora vodonika	11
Broj donora vodonika	3
Broj rotacionih veza	9
Particioni koeficijent^[4] (ALogP)	2,1
Rastvorljivost^[5] (logS, log(mol/L))	-4,9
Polarna površina^[6] (PSA, Å²)	187,9

Reference

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↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o.
↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573.
↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286.

Literatura

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Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.

Spoljašnje veze

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	Portal Medicina
	Portal Hemija

Sulfamazon na Wikimedijinoj ostavi

Sulfamazone

Šablon:Antibiotici inhibitori nukleinskih kiselina

Izvor: https://sh.wikipedia.org/w/index.php?title=Sulfamazon&oldid=41489666