SSBP1

Protein 1 vezivanja jednolančane DNK, mitohondrijski
	; PDB prikaz baziran na 1s3o.
Dostupne strukture
	1S3O, 2DUD, 3ULL
Identifikatori
Simboli	SSBP1; Mt-SSB; SOSS-B1; SSBP; mtSSB
Vanjski ID	OMIM: 600439 MGI: 1920040 HomoloGene: 74462 GeneCards: SSBP1 Gene
Ontologija gena
Molekulska funkcija	• hromatinsko vezivanje; • Protein vezivanja jednolančane DNK; • proteinsko vezivanje;
Ćelijska komponenta	• mitohondrija; • mitohondrijski nukleoid;
Biološki proces	• DNK replikacija; • pozitivna regulacija helikazne aktivnosti; • mitohondrijska morfogeneza;
Pregled RNK izražavanja
	podaci
Ortolozi

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Protein 1 vezivanja jednolančane DNK, mitohondrijski je protein koji je kod ljudi kodiran SSBP1 genom.^[1]^[2]

Reference

↑ Tiranti V, Rossi E, Ruiz-Carrillo A, Rossi G, Rocchi M, DiDonato S, Zuffardi O, Zeviani M (Jul 1995). „Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis”. Genomics 25 (2): 559–564. DOI:10.1016/0888-7543(95)80058-T. PMID 7789991.
↑ „Entrez Gene: SSBP1 single-stranded DNA binding protein 1”.

Literatura

Tiranti V, Rocchi M, DiDonato S, Zeviani M (1993). „Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB)”. Gene 126 (2): 219–225. DOI:10.1016/0378-1119(93)90370-I. PMID 8482537.
Yang C, Curth U, Urbanke C, Kang C (1997). „Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution”. Nat. Struct. Biol. 4 (2): 153–157. DOI:10.1038/nsb0297-153. PMID 9033597.
Schultz RA, Swoap SJ, McDaniel LD i dr.. (1998). „Differential expression of mitochondrial DNA replication factors in mammalian tissues”. J. Biol. Chem. 273 (6): 3447–3451. DOI:10.1074/jbc.273.6.3447. PMID 9452467.
Spelbrink JN, Toivonen JM, Hakkaart GA i dr.. (2000). „In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells”. J. Biol. Chem. 275 (32): 24818–24828. DOI:10.1074/jbc.M000559200. PMID 10827171.
Müller-Höcker J, Schäfer S, Li K (2002). „Immunocytochemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue”. Appl. Immunohistochem. Mol. Morphol. 9 (3): 276–280. DOI:10.1097/00022744-200109500-00013. PMID 11556757.
Takamatsu C, Umeda S, Ohsato T i dr.. (2002). „Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein”. EMBO Rep. 3 (5): 451–456. DOI:10.1093/embo-reports/kvf099. PMC 1084112. PMID 11964388.
Chen L, Segal D, Hukriede NA i dr.. (2002). „Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development”. Proc. Natl. Acad. Sci. U.S.A. 99 (22): 14320–14325. DOI:10.1073/pnas.212532399. PMC 137882. PMID 12381786.
Diez-Tascón C, Dodds KG, Crawford AM (2003). „Linkage mapping of the ovine single-stranded DNA-binding protein 1 (SSBP1) using microsatellite marker OARCDT7”. Anim. Genet. 33 (6): 468–468. DOI:10.1046/j.1365-2052.2002.00938_1.x. PMID 12464025.
Strausberg RL, Feingold EA, Grouse LH i dr.. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bayarsaihan D (2003). „SSDP1 gene encodes a protein with a conserved N-terminal FORWARD domain”. Biochim. Biophys. Acta 1599 (1–2): 152–5. DOI:10.1016/s1570-9639(02)00376-x. PMID 12479417.
Scherer SW, Cheung J, MacDonald JR i dr.. (2003). „Human chromosome 7: DNA sequence and biology”. Science 300 (5620): 767–772. DOI:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA i dr.. (2003). „The DNA sequence of human chromosome 7”. Nature 424 (6945): 157–164. DOI:10.1038/nature01782. PMID 12853948.
Gerhard DS, Wagner L, Feingold EA i dr.. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–2127. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Pocernich CB, Poon HF, Boyd-Kimball D i dr.. (2005). „Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat”. Brain Res. Mol. Brain Res. 133 (2): 299–306. DOI:10.1016/j.molbrainres.2004.10.024. PMID 15710247.

[pmid7789991-1] Tiranti V, Rossi E, Ruiz-Carrillo A, Rossi G, Rocchi M, DiDonato S, Zuffardi O, Zeviani M (Jul 1995). „Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis”. Genomics 25 (2): 559–564. DOI:10.1016/0888-7543(95)80058-T. PMID 7789991.

[entrez-2] „Entrez Gene: SSBP1 single-stranded DNA binding protein 1”.

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