Orotat reduktaza (NADPH)
| Orotat reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.15 | ||||||||
| CAS broj | 37255-27-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Orotat reduktaza (NADPH) (EC 1.3.1.15, orotatna reduktaza, dihidro-orotska dehidrogenaza, L-5,6-dihidro-orotat:NAD oksidoreduktaza, orotatna reduktaza (NADPH)) je enzim sa sistematskim imenom (S)-dihidroorotat:NADP oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-dihidroorotat NADP orotat NADPH H
Ovaj enzim vezuje FMN i FAD. Druga klasa 1 dihidroorotatnih dehidrogenaza koristi bilo fumarat (EC 1.3.98.1) ili NAD (EC 1.3.1.14) kao elektronski akceptor. Membanska klasa 2 dihidroorotatnih dehidrogenaza (EC 1.3.5.2) koristi hinon kao elektronski akceptor .
- ↑ Taylor, W.H., Taylor, M.L. and Eames, D.F. (1966). „Two functionally different dihydroorotic dehydrogenases in bacteria”. J. Bacteriol. 91: 2251-2256. PMID 4380263.
- ↑ Udaka, S. and Vennesland, B. (1962). „Properties of triphosphopyridine nucleotide-linked dihydroorotic dehydrogenase”. J. Biol. Chem. 237: 2018-2024. PMID 13923427.
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