Oksiracetam
Izgled
(IUPAC) ime | |||
---|---|---|---|
(RS)-2-(4-hidroksi-2-oksopikrolidin-1-il)acetamid | |||
Klinički podaci | |||
Identifikatori | |||
CAS broj | 62613-82-5 | ||
ATC kod | N06BX07 | ||
PubChem[1][2] | 4626 | ||
ChemSpider[3] | 4465 | ||
UNII | P7U817352G | ||
KEGG[4] | D07346 | ||
ChEMBL[5] | CHEMBL36633 | ||
Hemijski podaci | |||
Formula | C6H10N2O3 | ||
Mol. masa | 158,155 | ||
SMILES | eMolekuli & PubHem | ||
| |||
Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status | Unscheduled (US) | ||
Način primene | Oralno |
Oksiracetam je nootropni lek iz racetamne familije.[6][7]
Nekoliko životinjskih studija je pokazalo da je ova supstanca bezbedan čak i na visokim dozama tokom dužeg vremenskog perioda. Međutim, mehanizam dejstva racetamske familije lekova je se još uvek istražuje.
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948863.
- ↑ Malykh, A. G.; Sadaie, M. R. (2010). „Piracetam and Piracetam-Like Drugs”. Drugs 70 (3): 287–312. DOI:10.2165/11319230-000000000-00000. PMID 20166767.
- ↑ Gouliaev, A. H.; Senning, A. (1994). „Piracetam and other structurally related nootropics”. Brain Research Reviews 19 (2): 180–222. DOI:10.1016/0165-0173(94)90011-6. PMID 8061686.