Kempferol

Kaempferol
	3,5,7-Trihidroksi-2-(4-hidroksifenil)-4H-hromen-4-on
Drugi nazivi	Kaempherol; Robigenin; Pelargidenolon; Rhamnolutein; Rhamnolutin; Populnetin; Trifolitin; Kempferol; Swartziol;
Identifikacija
CAS registarski broj	520-18-3
PubChem	5280863
DrugBank	DB01852
KEGG	C05903
ChEMBL	CHEMBL150
Jmol-3D slike	Slika 1
SMILES
	C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
InChI
	InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H ; Kod: IYRMWMYZSQPJKC-UHFFFAOYSA-N
Svojstva
Molekulska formula	C15H10O6
Molarna masa	286,23 g/mol
Tačka topljenja	276–278 °C
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Kempferol je prirodni flavonol iz porodice flavonoida.

Hemija

Kempferol je žuta kristalna materija sa tačkom ključanja od 276–278 °C. On je neznatno rastvoran u vodi, ali je rastvoran u vrućem etanolu i dietil etru.

Prirodna pojava

On može da bude izolovan iz čaja,^[5] broklija, Delphinium, hamamelisa, grejpfruta, kupusa, kelja, pasulja, endivije, praziluka, paradajza, jagoda, grožđa, Prokelja, jabuka, i drugih biljnih izvora.

Kempferol i njegovi glukozidi se mogu izolovati iz metanolnog ekstrakta lista paprati Phegopteris connectilis.^[6]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948863. edit
↑ Jun Seong Park, Ho Sik Rho, Duck Hee Kim, and Ih Seop Chang (2006). „Enzymatic Preparation of Kaempferol from Green Tea Seed and Its Antioxidant Activity”. J. Agric. Food Chem. 54 (8): 2951–2956. DOI:10.1021/jf052900a. PMID 16608214.
↑ Klaus-Peter, Adam (1999). „Phenolic constituents of the fernPhegopteris connectilis”. Phytochemistry 52 (5): 929–934. DOI:10.1016/S0031-9422(99)00326-X.

Spoljašnje veze

Portal Hemija

Flavonoid composition of tea: Comparison of black and green teas Arhivirano 2007-06-21 na Wayback Machine-u

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948863. edit

[tea-5] Jun Seong Park, Ho Sik Rho, Duck Hee Kim, and Ih Seop Chang (2006). „Enzymatic Preparation of Kaempferol from Green Tea Seed and Its Antioxidant Activity”. J. Agric. Food Chem. 54 (8): 2951–2956. DOI:10.1021/jf052900a. PMID 16608214.

[6] Klaus-Peter, Adam (1999). „Phenolic constituents of the fernPhegopteris connectilis”. Phytochemistry 52 (5): 929–934. DOI:10.1016/S0031-9422(99)00326-X.

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