Butofilolol

Butofilolol
(IUPAC) ime
	(RS)-1-[2-[3-(tert-butilamino)-2-hidroksipropoksi]-5-fluorofenil]butan-1-on
Klinički podaci
Identifikatori
CAS broj	64552-17-6
ATC kod	nije dodeljen
PubChem	68838
ChemSpider	62071
UNII	4AZC6Y5A8G
ChEMBL	CHEMBL157443
Hemijski podaci
Formula	C17H26FNO3
Mol. masa	311,392 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 ; Key: NMBNQRJDEPOXCP-UHFFFAOYSA-N
Sinonimi	CM-6805
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Butofilolol (Cafide) je beta-blokator koji potencijalno može naći primenu u tretmanu primarne hipertenzije (visokog krvnog pritiska).^[5]^[6] Ovaj lek nije plasiran na tržište.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948863. edit
↑ Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). „Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man”. International journal of clinical pharmacology research 4 (3): 175–83. PMID 6149195.
↑ Toussain, P; Gay, G; Debry, G (1983). „Long-term hypotensive treatment by butofilolol”. Annales de cardiologie et d'angeiologie 32 (4): 277–83. PMID 6412614.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948863. edit

[5] Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). „Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man”. International journal of clinical pharmacology research 4 (3): 175–83. PMID 6149195.

[6] Toussain, P; Gay, G; Debry, G (1983). „Long-term hypotensive treatment by butofilolol”. Annales de cardiologie et d'angeiologie 32 (4): 277–83. PMID 6412614.

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