14-Etoksimetopon

14-Etoksimetopon
(IUPAC) ime
	3-Hidroksi-14-etoksi-5-metil-7,8-dihidro-4,5α-epoksi-17-metilmorfinan-6-on
Klinički podaci
Identifikatori
CAS broj	131575-04-7
ATC kod	nije dodeljen
PubChem	5487378
ChemSpider	4589341
Hemijski podaci
Formula	C20H25NO4
Mol. masa	343,42 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C20H25NO4/c1-4-24-20-8-7-15(23)18(2)19(20)9-10-21(3)14(20)11-12-5-6-13(22)17(25-18)16(12)19/h5-6,14,22H,4,7-11H2,1-3H3/t14-,18-,19?,20?/m1/s1 ; Key: LDTUYTORBPKTNO-HPJZBDCMSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

14-Etoksimetopon^[4] je opijatni analog koji je izveden iz metopona tako što je supstituisan sa jednom etoksi grupom u 14-poziciji. On je visoko potentan analgetik, koji je nekoliko stotina puta jači od morfina.^[5]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ US 6476044, Šablon:Cite patent/authors, "Use Of Morphine Derivatives As Medicaments For The Treatment Of Neuropathic Problems"
↑ Fürst, Z; Búzás, B; Friedmann, T; Schmidhammer, H; Borsodi, A (1993). „Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series”. European Journal of Pharmacology 236 (2): 209–15. DOI:10.1016/0014-2999(93)90591-5. PMID 8391457.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] US 6476044, Šablon:Cite patent/authors, "Use Of Morphine Derivatives As Medicaments For The Treatment Of Neuropathic Problems"

[5] Fürst, Z; Búzás, B; Friedmann, T; Schmidhammer, H; Borsodi, A (1993). „Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series”. European Journal of Pharmacology 236 (2): 209–15. DOI:10.1016/0014-2999(93)90591-5. PMID 8391457.

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