Vortioksetin
(Preusmjereno sa stranice Lu AA21004)
Vortioksetin (Lu AA21004) je eksperimentalni lek, koji je u razvoju za tretman kliničke depresije i generalizovanog anksioznog poremećaja.[5][6][7].
| |||
| |||
| (IUPAC) ime | |||
|---|---|---|---|
| 1-(2-((2,4-dimetilfenil)tio)fenil)piperazin | |||
| Klinički podaci | |||
| Identifikatori | |||
| CAS broj | 508233-74-7 | ||
| ATC kod | nije dodeljen | ||
| PubChem[1][2] | 9966051 | ||
| ChemSpider[3] | 26286009 | ||
| KEGG[4] | D10184 
| ||
| Hemijski podaci | |||
| Formula | C18H22N2S | ||
| Mol. masa | 298,45 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Sinonimi | Lu AA21004 | ||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
| Način primene | Oralno | ||
Reference
uredi- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Jancin B (December 2009). „Lu AA21004 Looks Promising for Depression”. Clinical Psychiatry News 37 (12): 24–25. DOI:10.1016/S0270-6644(09)70441-2.
- ↑ „Lundbeck seeks European approval of antidepressant”. Arhivirano iz originala na datum 2013-12-03. Pristupljeno 2014-04-05.
- ↑ „Application filed to the U.S. Food and Drug Administration for approval of its antidepressant, vortioxetine”. Arhivirano iz originala na datum 2013-12-03. Pristupljeno 2014-04-05.
