CELLINK

Mark your calendar for an exciting webinar on October 23! Featuring Professor Zaozao Chen from Southeast University, who will present his insightful work on organ-on-a-chip models. 📅 Date: October 23rd, 2:00 pm CST (China Standard Time), 3:00 pm JST, 11:30 am IST, 8 am CEST 🎤 Speaker: Professor Zaozao Chen, Southeast University Professor Chen will present more on how they combine organ-on-a-chip technology with 3D bioprinting to develop advanced biomimetic in vitro models. These models can offer a more accurate simulation of human biology, enabling significant advancements in drug discovery. Take the chance to learn more about how biomimetic models mimic organ-level physiology, and how these models can be used in drug discovery and as alternative testing models. Register here: https://lnkd.in/dBMRzwsE #Bioprinting #TissueEngineering #OrganOnAChip #DrugDiscovery #CancerResearch #AlternativeToAnimalTesting

It has been a busy first day so far at #ELRIGDrugDiscovery2024, and we have enjoyed sharing to attendees how bioprinting and 3D cell culture can improve their drug discovery workflows. Come by Booth B7 to learn more about what 3D bioprinting can do to improve your search for promising drug candidates, and meet with our bioprinting experts Andrew Ridley, Isabella Bondesson and Avijit Minocha. On showcase are our two workhorse bioprinters, the BIO X and the BIONOVA X. See them in action at the booth! (And don't miss our friends, CYTENA and DISPENDIX displaying their innovative systems next to us!) We look forward to seeing you! #3dbioprinting #drugdiscovery #3dcellculture #tissueengineering

The deadlines are rapidly closing in for Bioprinting Ignited x Greece! Join us for exciting presentations from bioprinting experts across the academic world. Speakers: Prof. Dimitrios A. Lamprou, Queen's University Belfast Prof. Dimitris Fatouros, School of Pharmacy, Aristotle University of Thessaloniki (AUTH) Prof. Andreana Assimopoulou, School of Chemical Engineering, AUTH Prof. Xanthippi Chatzistavrou, School of Chemical Engineering, AUTH Dr. Ioanna Koumentakou, Department of Chemistry, Dr. Bikiaris Lab, AUTH ... as well as sessions from experts from our internal team. Take the chance to be inspired, see the power of bioprinters, and network with industry experts. Register here: https://lnkd.in/dTDbjhj8 #BioprintingIgnited #3DBioprinting #Conference #Workshop #Thessaloniki #Greece

It's a little less than one month left until Bioprinting Ignited x Greece kicks off! Don't miss registering for an exciting conference and workshop! Our list of talented speakers will provide valuable bioprinting insights regardless if you're an experienced pro, just getting started, or curiously looking through the window. If you want to present your work, submit your abstract by October 4! We look forward to seeing you there. Learn more and register: https://lnkd.in/dTDbjhj8 #BioprintingIgnited #3DBioprinting #Conference #Workshop #Thessaloniki #Greece

It's the first day of EUSAAT 2024 Congress, and we are eager to share to the European research community how our industry-leading 3D bioprinting technologies provide an alternative to animal testing. Stop by our booth, where our bioprinting experts Dr. Cathrin Schulz and Flore-Anne Poujade are happy to discuss how 3D bioprinting can provide an excellent animal testing alternative for your research. See both the BIO X and the LUMEN X in action at the booth – we look forward to seeing you there! #animaltesting #alternativestoanimaltesting #bioprinting #tissueengineering

Last week, we wrapped up the CELLINK Global Sales Summit here in Sweden, where our incredible team members from around the world came together. Over the course of three inspiring days, we had the opportunity to meet face-to-face, share ideas, and engage in impactful meetings, trainings, and collaborative sessions. It was an enriching experience to connect in person, and strengthen our global bonds. Looking forward to seeing the impact of these efforts unfold! #CELLINK #GlobalTeam #SalesSummit #Innovation #Collaboration #Bioprinting

As 3D cell culture is becoming easier to use, more and more researchers are seeking to take advantage of the benefits. 3D cell culture allows cells to interact with other cells and an extracellular matrix (ECM), in three dimensions. This differs from traditional monolayer cell culture where cells interact only on a monolayer plane. Technological advancements in 3D bioprinting hardware and software have democratized the use of 3D cell culture, enabling more researchers to take part in the 3D revolution. Compared to conventional culturing methods, 3D cell culture brings: - More biomimetic and translational models - Improved cellular interactions - Better recapitulation of tissues Learn more about 3D cell culture in our blog: https://lnkd.in/dp7bE_Us #3DCellCulture #CellCulture #Biology #CELLINK

Summer is nearing its end in the Northern Hemisphere, and with it an annual bump in skin cancers such as malignant melanoma. Creating in vitro tissue models of skin cancers that represent the tumor’s microenvironment will enable developments in melanoma therapy, as well as more accurate drug screening. Last week, the Centre of Excellence for Pharmaceutical Sciences at North West University Potchefstroom published an article titled “Pneumatic extrusion bioprinting-based high throughput fabrication of a melanoma 3D cell culture model for anti-cancer drug screening”. Maryke de Villiers et al set out to develop a simple, highly reproducible approach to developing a A375 melanoma 3D cell culture model. To do this, the research team used the BIO X 3D bioprinter as well as CELLINK’s GelMA A bioink. After further optimizing the printing parameters, the team printed cell-laden GelMA A droplets into a 96-well plate. Prior to drug-dosing, the team also created a 2D cell culture model. The cells showed a steadier proliferation rate in the 3D cell culture, and tended to aggregate into spheroids, whereas the 2D cell culture formed monolayer cell sheets. To evaluate the efficacy of the models, the team compared the drug responses in the two different cell culture types. The results indicate that the spheroids in the 3D cell culture model exhibited a higher level of drug resistance. This study highlights that 3D cell culture models – while a better environment for cells to thrive in – don’t add complexity to currently used assays. And that the 3D cell culture models have considerable potential for drug screening applications. Read the publication here: https://lnkd.in/dqkzDQ8j #3Dbioprinting #PublicationSpotlight #CancerResearch #Melanoma #DrugScreening

The BIONOVA X is our high-throughput DLP bioprinter, printing directly into well plates, enabling the creation of precise, complex biomimetic models. With bioprinting – you have the power to create what your research requires. For example, with multi-stiffness and multi-material capabilities, the BIONOVA X can create highly accurate diseased models that capture the smallest changes that would occur from the disease. This makes BIONOVA X an excellent option in some drug screening applications. Scroll through the slides below to learn more about the BIONOVA X and how it can help your research. #3dbioprinting #tissueengineering #BIONOVAX

Contracting the Zika Virus (ZIKV) comes with a risk of severe pregnancy complications, and has been linked to Guillain–Barré syndrome, an autoimmune disorder. In a paper from Shah et al. at Mercer University, titled “Buccal Administration of a Zika Virus Vaccine Utilizing 3D-Printed Oral Dissolving Films in a Mouse Model”, the researchers present a novel method for a pain-free, topical, delivery of a vaccine against ZIKV. Shah et al. used an INKREDIBLE 3D bioprinter to print oral dissolving films (ODFs). The ODFs consisted of various biodegradable biopolymers as well as ZIKV vaccine microparticles as previously developed by the group. Within mouse studies, the vaccine showed promising results that suggests potential protection against future Zika infections. While this proof-of-concept research shows great promise, the results also indicate that multiple vaccine doses may be necessary to achieve long-term immunity. In future research, the group will assess the vaccine’s neutralization ability in mice against a lethal dose of ZIKV. The researchers hope that the use of a pain-free vaccine alternative, like bioprinted ODFs, can contribute to enhanced regulatory compliance. We look forward to continuing to follow the group’s novel, innovative work. Read the publication: https://lnkd.in/daicCbiS #PublicationSpotlight #3DBioprinting #DrugDelivery #ZikaVirus #VaccineResearch