套件：pirs（2.0.2 dfsg-8）
Profile based Illumina pair-end Reads Simulator
The program pIRS can be used for simulating Illumina PE reads, with a series of characters generated by Illumina sequencing platform, such as insert size distribution, sequencing error(substitution, insertion, deletion), quality score and GC content-coverage bias.
The insert size follows a normal distribution, so users should set the mean value and standard deviation. Usually the standard deviation is set as 1/20 of the mean value. The normal distribution by Box-Muller method is simulated.
The program simulates sequencing error, quality score and GC content- coverage bias according to the empirical distribution profile. Some default profiles counted from lots of real sequencing data are provided.
To simulate reads from diploid genome, users should simulate the diploid genome sequence firstly by setting the ratio of heterozygosis SNP, heterozygosis InDel and structure variation.
其他與 pirs 有關的套件
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- dep: fonts-liberation
- Fonts with the same metrics as Times, Arial and Courier
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- dep: gnuplot
- Command-line driven interactive plotting program.
同時作為一個虛擬套件由這些套件填實： gnuplot-nox, gnuplot-qt, gnuplot-x11
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- dep: libc6 (>= 2.4)
- GNU C 函式庫：共用函式庫
同時作為一個虛擬套件由這些套件填實： libc6-udeb
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- dep: libgcc1 (>= 1:4.2)
- GCC 支援函式庫
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- dep: libgomp1 (>= 4.9)
- GCC OpenMP (GOMP) support library
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- dep: libgzstream0 (>= 1.5 dfsg)
- provide functionality of zlib C-library in a C iostream
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- dep: libstdc 6 (>= 5.2)
- GNU Standard C Library v3
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- dep: pirs-profiles
- profile basd Illumina pair-end Reads Simulator (profile data)
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- dep: zlib1g (>= 1:1.2.0.2)
- 壓縮函式庫 - 跑程式時用(runtime)