Multiple alignment program for amino acid or nucleotide sequences
MAFFT is a multiple sequence alignment program which offers three
accuracy-oriented methods:
* L-INS-i (probably most accurate; recommended for <200 sequences;
iterative refinement method incorporating local pairwise alignment
information),
* G-INS-i (suitable for sequences of similar lengths; recommended for
<200 sequences; iterative refinement method incorporating global
pairwise alignment information),
* E-INS-i (suitable for sequences containing large unalignable regions;
recommended for <200 sequences),
and five speed-oriented methods:
* FFT-NS-i (iterative refinement method; two cycles only),
* FFT-NS-i (iterative refinement method; max. 1000 iterations),
* FFT-NS-2 (fast; progressive method),
* FFT-NS-1 (very fast; recommended for >2000 sequences; progressive
method with a rough guide tree),
* NW-NS-PartTree-1 (recommended for ∼50,000 sequences; progressive
method with the PartTree algorithm).
