Daniela Begolo
Amsterdam, Noord-Holland, Nederland
2K volgers
Meer dan 500 connecties
Info
VC investments in early-stage healthcare start-ups • Molecular biologist with research experience in small molecules studies and drug target deconvolution
Ervaring
Opleiding
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Activiteiten en verenigingen:Student representative - Representative within the Master degree’s decision board, organization of scientific outreach activities
Advanced cell and molecular biology, organic and bioorganic chemistry, nanotechnologies, structural biology, immunology and immunological techniques, industrial production
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Cell and molecular biology, biological and biotechnological techniques, chemistry applied to biotechnologies, immunology and pathology, bioinformatics, patents, bioethics
Publicaties
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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing
Submitted
Research paper describing mode of action studies of AN7973 and other small molecules belonging to the benzoxaborole compound series. In particular, the effect on mRNA trans-splicing in the eukaryiotic parasite Trypanosoma brucei.
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Discovering the mechanism of action of novel compounds that target unicellular eukaryotic parasites
Wiley Online Library
Book chapter of "Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery: From Metabolism to Drug Discovery"
Overview of different techniques for drug mode of action studies in eukaryotic parasites. -
Drug target identification using a trypanosome over-expression library
Antimicrobial Agents and Chemotherapy
Research paper. Proof of concept study to demonstrate the efficacy in using an over-expression library for identifying drug targets in Trypanosoma brucei.
Andere auteurs
Talen
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