(Q73846452)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

title

Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

1

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7 November 2019

author name string

Matzke GR

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

Adedoyin A

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

Porter JA

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

Branch RA

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

publication date

1 October 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

7 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

365-376

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

Liver blood flow, antipyrine clearance, and antipyrine metabolite formation clearance in patients with chronic active hepatitis and alcoholic cirrhosis

7 November 2019

cites work

1 reference

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Influence of diet and nutritional status on drug metabolism

7 January 2021

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Assessment of liver metabolic function. Clinical implications

7 January 2021

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A 'cocktail' strategy to assess in vivo oxidative drug metabolism in humans

7 January 2021

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Interindividual variations in drug disposition. Clinical implications and methods of investigation

7 January 2021

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Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva.

7 January 2021

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Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

7 January 2021

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Single-dose disulfiram inhibition of chlorzoxazone metabolism: a clinical probe for P450 2E1

7 January 2021

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Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population

7 January 2021

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The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

7 January 2021

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Genetic polymorphism of S-mephenytoin hydroxylation

7 January 2021

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The disposition of dapsone in cirrhosis

7 January 2021

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Activity of oxidative routes of metabolism of debrisoquin, mephenytoin, and dapsone is unrelated to the pathogenesis of vinyl chloride-induced disease

7 January 2021

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Simplified phenotyping with dextromethorphan by thin-layer chromatography: application to clinical laboratory screening for deficiencies in oxidative drug metabolism

7 January 2021

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Scleroderma is associated with differences in individual routes of drug metabolism: a study with dapsone, debrisoquin, and mephenytoin

7 January 2021

1 reference

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Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography

7 January 2021

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The contribution of N-hydroxylation and acetylation to dapsone pharmacokinetics in normal subjects

7 January 2021

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Improved high-performance liquid chromatographic determination of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism

7 January 2021

1 reference

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Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

High-performance liquid chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in serum: a tool for indirect evaluation of cytochrome P4502E1 activity in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo*

7 January 2021

1 reference

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N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

7 January 2021

1 reference

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Pharmacokinetics and metabolism of quinidine in extensive and poor metabolisers of sparteine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Relationship between the metabolism of antipyrine, hexobarbital and theophylline in patients with liver disease as assessed by a 'cocktail' approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Relationship between the metabolism of antipyrine, hexobarbitone and theophylline in man as assessed by a 'cocktail' approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients

7 January 2021

1 reference

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Metronidazole and antipyrine as probes for the study of foreign compound metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Influence of renal failure on cytochrome P 450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

The relationship between phenazone (antipyrine) metabolite formation and theophylline metabolism in healthy and frail elderly women

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Comparison of hepatic drug-oxidizing activity after simultaneous administration of two probe drugs, caffeine and trimethadione, to human subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: a cocktail and extended phenotyping assessment trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine

7 January 2021

1 reference

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Rapid screening for polymorphisms in dextromethorphan and mephenytoin metabolism

7 January 2021

1 reference

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Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans

7 January 2021

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Lack of pharmacokinetic interaction between nifedipine, sparteine and phenytoin in man.

7 January 2021

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Cocktail strategy: complications and limitations

7 January 2021

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The ability to 4-hydroxylate debrisoquine is related to recurrence of bladder cancer

7 January 2021

1 reference

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Interaction between two probes used for phenotyping cytochromes P4501A2 (caffeine) and P4502E1 (chlorzoxazone) in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0009-9236(97)90114-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-9236(97)90114-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9357387 AND SRC:MED&resulttype=core&format=json

7 November 2019

1 reference