(Q73692223)

English

Molecular Modeling-guided Mutagenesis of the Extracellular Part of gp130 Leads to the Identification of Contact Sites in the Interleukin-6 (IL-6)·IL-6 receptor·gp130 Complex

scientific article published on September 19, 1997

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

Molecular Modeling-guided Mutagenesis of the Extracellular Part of gp130 Leads to the Identification of Contact Sites in the Interleukin-6 (IL-6)·IL-6 receptor·gp130 Complex (English)

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

author name string

U. Horsten

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

G. Müller-Newen

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

C. Gerhartz

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

A. Wollmer

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

J. Wijdenes

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

P. C. Heinrich

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

J. Grötzinger

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

language of work or name

0 references

publication date

1 September 1997

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

19 September 1997

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9295319

15 November 2024

full work available at URL

http://www.jbc.org/content/272/38/23748.full.pdf

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9295319

15 November 2024

https://api.elsevier.com/content/article/PII:S0021925819658515?httpAccept=text/xml

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

https://api.elsevier.com/content/article/PII:S0021925819658515?httpAccept=text/plain

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.272.38.23748

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

272

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

38

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

23748-23757

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

Interleukin-6 and the acute phase response

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Interleukin-6 and its receptor: a paradigm for cytokines

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Molecular cloning and expression of an IL-6 signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL-6 and the IL-6 receptor

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

The three carboxy-terminal amino acids of human interleukin-6 are essential for its biological activity

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Combining two mutations of human interleukin-6 that affect gp130 activation results in a potent interleukin-6 receptor antagonist on human myeloma cells

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Participation of Two Ser-Ser-Phe-Tyr Repeats in Interleukin-6 (IL-6)-Binding Sites of the Human IL-6 Receptor

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Structural and functional epitopes in the growth hormone receptor complex

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

A hot spot of binding energy in a hormone-receptor interface

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074/JBC.272.38.23748

21 January 2018

Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130

25

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector.

26

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization

27

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Journal of Cell Biology

31

265

1216

author name string

Graeve

publication date

1989

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

36

1 reference

10.1074/JBC.272.38.23748

https://api.crossref.org/works/10.1074/JBC.272.38.23748

15 November 2024

Identifiers

10.1074/JBC.272.38.23748

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9295319 AND SRC:MED&resulttype=core&format=json

6 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q73692223&oldid=2275218441"