(Q60272299)

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Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

scientific article published on 01 June 1999

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Europe PubMed Central

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9 December 2019

Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1 (English)

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9 December 2019

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Marcin Kortylewski

1

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9 December 2019

Ursula Klingmüller

5

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9 December 2019

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Heinrich PC

2

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9 December 2019

Mackiewicz A

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9 December 2019

Schniertshauer U

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9 December 2019

Nakajima K

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9 December 2019

Hirano T

7

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9 December 2019

Horn F

8

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9 December 2019

Behrmann I

9

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9 December 2019

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1 June 1999

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9 December 2019

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9 December 2019

18

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9 December 2019

25

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9 December 2019

3742-3753

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9 December 2019

Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector.

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G1 phase arrest by the phosphatidylinositol 3‐kinase inhibitor LY 294002 is correlated to up‐regulation of p27Kip1 and inhibition of G1 CDKs in choroidal melanoma cells

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A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor

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Protein expression of the cell-cycle inhibitor p27Kip1 in malignant melanoma: inverse correlation with disease-free survival

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

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STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

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The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

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Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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Human melanoma: development and progression

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Interleukin 6 and its Receptor: Ten Years Later

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Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

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Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells

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Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6

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Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression

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Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association

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Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation

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STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

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Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

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Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

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A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

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Association of Stat3-Dependent Transcriptional Activation of p19INK4Dwith IL-6-Induced Growth Arrest

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Identifiers

10.1038/SJ.ONC.1202708

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391682 AND SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391682 AND SRC:MED&resulttype=core&format=json

9 December 2019

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