(Q5198251)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q00526

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/K7EJ83

Protein kinase domain, protein family

1 reference

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

inferred from protein domain or family

2 references

13 November 2019

17 September 2016

2 references

13 November 2019

21 March 2016

language of work or name

English

molecular function

protein serine/threonine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

cyclin-dependent protein serine/threonine kinase activity

A family of human cdc2-related protein kinases

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

protein binding

4 references

8 April 2019

The protein interaction landscape of the human CMGC kinase group

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

8 April 2019

Cyclin C is a haploinsufficient tumour suppressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

8 April 2019

CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

8 April 2019

Cyclin C/cdk3 promotes Rb-dependent G0 exit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

cyclin binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

cyclin-dependent protein kinase holoenzyme complex

cell component

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

nucleus

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

biological process

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

G0 to G1 transition

1 reference

8 April 2019

Cyclin C/cdk3 promotes Rb-dependent G0 exit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

cellular response to DNA damage stimulus

IDA

1 reference

8 April 2019

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

IDA

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

1 reference

8 April 2019

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

positive regulation of cell population proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

response to organic substance

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

regulation of G2/M transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

regulation of gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00526&geneProductId=UniProtKB:Q00526

1 reference

31 January 2018

G1/S transition of mitotic cell cycle

1 reference

8 April 2019

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

regulation of cell cycle

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00526

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:K7EJ83

1 reference

8 April 2019

physically interacts with

at-7519

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL445813

AZD5438

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL488436

Gene Atlas image

PBB GE CDK3 207188 at fs.png
732 × 530; 12 KB

0 references

exact match

http://purl.uniprot.org/uniprot/Q00526

1 reference

D08.811.913.696.620.682.700.646.500.812

Identifiers.org

Identifiers

MeSH descriptor ID

D056849

subject named as

Cyclin-Dependent Kinase 3

0 references

MeSH tree code

0 references

D12.776.167.200.387

0 references

D12.776.476.563.646.500.812

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

21 March 2016

language of work or name

1 reference

1 reference

1 reference

1 reference

1 reference

22 October 2015

http://www.uniprot.org/uniprot/Q00526.txt?163

UMLS CUI

C2607946

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023