(Q46147419)

19 December 2017

title

Antigen-induced B-cell death and elimination during germinal-centre immune responses (English)

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19 December 2017

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Shokat KM

1

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19 December 2017

Goodnow CC

series ordinal

2

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19 December 2017

language of work or name

English

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publication date

1 May 1995

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19 December 2017

published in

Nature

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19 December 2017

volume

375

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19 December 2017

issue

6529

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19 December 2017

page(s)

334-338

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19 December 2017

Variability in the Lambda Light Chain Sequences of Mouse Antibody

cites work

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7 January 2021

Somatic generation of antibody diversity

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7 January 2021

Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways

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7 January 2021

Intraclonal generation of antibody mutants in germinal centres

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7 January 2021

Maturation of the immune response in germinal centers

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7 January 2021

Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity

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7 January 2021

The role of clonal selection and somatic mutation in autoimmunity

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7 January 2021

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

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7 January 2021

The role of somatic mutation in the pathogenic anti-DNA response

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7 January 2021

Profound specific suppression by antigen of persistent IgM, IgG, and IgE antibody production

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7 January 2021

Soluble antigen profoundly reduces memory B-cell numbers even when given after challenge immunization

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7 January 2021

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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7 January 2021

The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site

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7 January 2021

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

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7 January 2021

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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7 January 2021

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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7 January 2021

Mechanism of antigen-driven selection in germinal centres

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7 January 2021

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7 January 2021

Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction

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7 January 2021

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

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7 January 2021

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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7 January 2021

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

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7 January 2021

Repetitive proteins and genes of malaria

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7 January 2021

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

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7 January 2021

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells

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7 January 2021

Identifiers

DOI

10.1038/375334A0

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19 December 2017

Dimensions Publication ID

1015288677

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19 December 2017