(Q45866583)

17 December 2017

title

Development of a hypoxia-responsive vector for tumor-specific gene therapy (English)

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17 December 2017

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Shibata T

1

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17 December 2017

Giaccia AJ

series ordinal

2

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17 December 2017

Brown JM

series ordinal

3

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17 December 2017

publication date

1 March 2000

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

7

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17 December 2017

issue

6

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17 December 2017

page(s)

493-498

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17 December 2017

In vivo gene therapy for prostate cancer: preclinical evaluation of two different enzyme-directed prodrug therapy systems delivered by identical adenovirus vectors

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Targeting gene expression to hypoxic tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.GT.3301124

Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.GT.3301124

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

21 January 2018

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https://api.crossref.org/works/10.1038/SJ.GT.3301124

The regulated expression of erythropoietin by two human hepatoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Sequencing of the human vascular endothelial growth factor (VEGF) 3' untranslated region (UTR): conservation of five hypoxia-inducible RNA-protein binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Tissue oxygen distribution in head and neck cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

7 January 2021

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

7 January 2021

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways

1 reference

https://api.crossref.org/works/10.1038/SJ.GT.3301124

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301124

1 reference

17 December 2017

Dimensions Publication ID

1031476597

0 references

1 reference

17 December 2017