(Q45736205)

15 December 2017

title

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness (English)

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15 December 2017

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36

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Shinya Yamanaka

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Hiroyuki Hioki

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William L. Klein

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object named as

William L Klein

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11

Kazutoshi Takahashi

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Naohiro Egawa

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28

Satoko Yamawaki

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Motoko Naitoh

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Keisuke Okita

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Kayoko Tsukita

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Takayuki Kondo

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Masashi Asai

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Yumiko Kutoku

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Yutaka Ohsawa

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Yoshihide Sunada

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Keiko Imamura

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Naoki Yahata

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Isao Asaka

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Takashi Aoi

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Akira Watanabe

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Kaori Watanabe

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Chie Kadoya

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Rie Nakano

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Dai Watanabe

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Kei Maruyama

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Osamu Hori

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Satoshi Hibino

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Tominari Choshi

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Tatsutoshi Nakahata

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Takeshi Kaneko

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Katsuhiro Yoshikawa

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Shigehiko Suzuki

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Ryuji Hata

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Shu-Ichi Ueno

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Tsuneyoshi Seki

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Kazuhiro Kobayashi

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Tatsushi Toda

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Kazuma Murakami

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Hiroshi Mori

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Takashi Asada

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Ryosuke Takahashi

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Nobuhisa Iwata

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15 December 2017

Haruhisa Inoue

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15 December 2017

language of work or name

English

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publication date

21 February 2013

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15 December 2017

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15 December 2017

volume

12

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15 December 2017

issue

4

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15 December 2017

page(s)

487-496

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describes a project that uses

15 December 2017

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A more efficient method to generate integration-free human iPS cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NMETH.1591

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE10821

Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Amyloid &#946;-Peptide [1-42]-Associated Free Radical-Induced Oxidative Stress And Neurodegeneration in Alzheimers Disease Brain: Mechanisms and Consequences

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Monoclonal antibody against the turn of the 42-residue amyloid β-protein at positions 22 and 23

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Monoclonal antibodies that target pathological assemblies of Abeta

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

ADDLs and the signaling web that leads to Alzheimer's disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Modeling familial Alzheimer's disease with induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Specification of transplantable astroglial subtypes from human pluripotent stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Effect of pathogenic mutations on the structure and dynamics of Alzheimer's A beta 42-amyloid oligomers.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

DHA inhibits ER Ca2 release and ER stress in astrocytes following in vitro ischemia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

A specific amyloid-beta protein assembly in the brain impairs memory

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Clinical course of patients with familial early-onset Alzheimer's disease potentially lacking senile plaques bearing the E693Δ mutation in amyloid precursor protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Neurodegenerative diseases and oxidative stress

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2013.01.009

Identifiers

DOI

10.1016/J.STEM.2013.01.009

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15 December 2017

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