(Q44519392)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

6 November 2019

title

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis (English)

1 reference

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X-ray scattering technique

6 November 2019

main subject

1 reference

10

1 reference

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6 November 2019

Paul Mould

1

1 reference

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6 November 2019

author name string

Emlyn J H Symonds

2

1 reference

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6 November 2019

Patrick A Buckley

3

1 reference

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6 November 2019

J Günter Grossmann

4

1 reference

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6 November 2019

Paul A McEwan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

6 November 2019

Stephanie J Barton

6

1 reference

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6 November 2019

Janet A Askari

7

1 reference

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6 November 2019

Susan E Craig

8

1 reference

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6 November 2019

Jordi Bella

9

1 reference

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6 November 2019

language of work or name

English

0 references

publication date

19 July 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

6 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

6 November 2019

issue

41

1 reference

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6 November 2019

page(s)

39993-39999

1 reference

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In vivo functions of integrins: lessons from null mutations in mice

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Integrins: bidirectional, allosteric signaling machines

21 January 2018

1 reference

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Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble

21 January 2018

1 reference

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Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis

21 January 2018

1 reference

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Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.

21 January 2018

1 reference

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Integrin activation takes shape

21 January 2018

1 reference

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Integrin activation and structural rearrangement

21 January 2018

1 reference

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Integrin structure: new twists and turns in dynamic cell adhesion

21 January 2018

1 reference

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Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation

21 January 2018

1 reference

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

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Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Generation of a minimal alpha5beta1 integrin-Fc fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

The N-terminal extension of rusticyanin is not responsible for its acid stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Determination of domain structure of proteins from X-ray solution scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Advances in structure analysis using small-angle scattering in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Low resolution meets high: towards a resolution continuum from cells to atoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2 , Mg2 , and Ca2 .

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

A minimized human integrin alpha(5)beta(1) that retains ligand recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

In vitro selection of fibronectin gain-of-function mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Synergistic activity of the ninth and tenth FIII domains of human fibronectin depends upon structural stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

The eighth FIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth FIII domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Distinct activation states of alpha5beta1 integrin show differential binding to RGD and synergy domains of fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Force measurements of the alpha5beta1 integrin-fibronectin interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Anti-integrin as novel drug-discovery targets: potential therapeutic and diagnostic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Mapping functional residues onto integrin crystal structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Automated matching of high- and low-resolution structural models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Molecular Basis of Ligand Recognition by Integrin α5β1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M304627200

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M304627200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12871973 AND SRC:MED&resulttype=core&format=json

6 November 2019

1 reference