(Q44485247)

3 December 2017

title

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis (English)

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3 December 2017

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Girish V Putcha

1

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3 December 2017

Siyuan Le

2

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3 December 2017

Stephan Frank

3

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3 December 2017

Cagri G Besirli

4

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3 December 2017

Kim Clark

5

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3 December 2017

Boyang Chu

6

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3 December 2017

Shari Alix

7

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3 December 2017

Richard J Youle

8

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3 December 2017

Art LaMarche

9

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3 December 2017

Anna C Maroney

10

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3 December 2017

Eugene M Johnson

11

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3 December 2017

language of work or name

English

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publication date

1 June 2003

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3 December 2017

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3 December 2017

volume

38

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3 December 2017

issue

6

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3 December 2017

page(s)

899-914

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

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7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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7 January 2021

Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

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7 January 2021

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Cellular distribution of c-Jun and c-Fos in rat lung before and after bleomycin induced injury

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Techniques in the tissue culture of rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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7 January 2021

c-Jun N-terminal kinase specifically phosphorylates p66ShcA at serine 36 in response to ultraviolet irradiation

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https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Evidence for a role of mixed lineage kinases in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Localization of activator protein-1 complex with DNA binding activity in mitochondria of murine brain after in vivo treatment with kainate.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Mitogen-activated protein kinase kinase 7 is activated during low potassium-induced apoptosis in rat cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(03)00355-6

7 January 2021

10.1016/S0896-6273(03)00355-6

Identifiers

DOI

1 reference

3 December 2017

1 reference