(Q43672870)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

title

Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Pimaricin, streptomyces chattanoogensis

1 reference

inferred from

reverse claim

Streptomyces natalensis

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

author name string

M V Mendes

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

E Recio

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

R Fouces

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

R Luiten

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

J F Martín

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 July 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

full work available at URL

9 November 2019

http://www.cell.com/article/S1074552101000333/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(01)[email protected]

published in

Chemistry and Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

635-644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11451665 AND SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(01)[email protected]

access restriction status

open access

1 reference

inferred from online access status

cites work

The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Polyketide synthesis: prospects for hybrid antibiotics

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Genetic Contributions to Understanding Polyketide Synthases

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Modular organization of genes required for complex polyketide biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis byStreptomyces antibioticus

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Characterization and expression of a P-450-like mycinamicin biosynthesis gene using a novel Micromonospora-Escherichia coli shuttle cosmid vector

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Cloning and heterologous expression of the epothilone gene cluster.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Combinatorial biosynthesis for new drug discovery

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Engineering of modular polyketide synthases to produce novel polyketides

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Combinatorial biosynthesis of erythromycin and complex polyketides

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

New derivatives of the Streptomyces temperate phage phi C31 useful for the cloning and functional analysis of Streptomyces DNA.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Combinatorial approaches to polyketide biosynthesis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

An erythromycin analog produced by reprogramming of polyketide synthesis

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Engineered Biosynthesis of Structurally Diverse Tetraketides by a Trimodular Polyketide Synthase

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

A hybrid modular polyketide synthase obtained by domain swapping

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Precursor-Directed Biosynthesis of Erythromycin Analogs by an Engineered Polyketide Synthase

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Engineered intermodular and intramodular polyketide synthase fusions

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Engineering broader specificity into an antibiotic-producing polyketide synthase

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021

Restriction mapping of the DNA of the Streptomyces temperate phage øC31 and its derivatives

1 reference

https://api.crossref.org/works/10.1016/S1074-5521(01)50033-3

7 January 2021