(Q42944177)

English

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

scientific article published on November 2000

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity (English)

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

2

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

author name string

M Bemark

1

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

H J Kim

3

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

C Berek

4

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

R A Cosgrove

5

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

M S Neuberger

6

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

language of work or name

0 references

publication date

1 November 2000

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

192

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

10

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

1509-1514

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Association of terminal deoxynucleotidyl transferase with Ku

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Ku80 is required for immunoglobulin isotype switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Somatic Hypermutation Introduces Insertions and Deletions into Immunoglobulin V Genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

A severe combined immunodeficiency mutation in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Induction by antigen of intrathymic apoptosis of CD4 CD8 TCRlo thymocytes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

27 May 2018

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

16 August 2018

Immunoglobulin gene hypermutation in germinal centers is independent of the RAG-1 V(D)J recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

16 August 2018

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193187

3 November 2018

Rapid induction of anti-idiotypic responses to unmodified monoclonal antibodies from syngeneic mice following primary immunization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11085752

12 December 2020

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Identifiers

10.1084/JEM.192.10.1509

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

ResearchGate publication ID

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