(Q423660)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04141

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04141

image

GMCSF Crystal Structure.rsh.png
900 × 750; 236 KB

media legend

Structure cristalline du GM-CSF telle que publiée dans la Protein Data Bank (French)

0 references

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

1 reference

10 September 2018

cytokine activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

3 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

27 March 2018

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

cytokine activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

IBA

cell component

extracellular region

intracellular membrane-bounded organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

1 reference

8 April 2019

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

3 references

27 March 2018

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

27 March 2018

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

negative regulation of cytolysis

IBA

biological process

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

positive regulation of macrophage derived foam cell differentiation

1 reference

8 April 2019

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

1 reference

8 April 2019

positive regulation of podosome assembly

1 reference

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

positive regulation of interleukin-23 production

1 reference

8 April 2019

Salmonella induced IL-23 and IL-1beta allow for IL-12 production by monocytes and Mphi1 through induction of IFN-gamma in CD56 NK/NK-like T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

positive regulation of gene expression

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

embryonic placenta development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

epithelial fluid transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

macrophage activation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

cellular response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

1 reference

8 April 2019

monocyte differentiation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

response to fluid shear stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

response to silicon dioxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

neutrophil differentiation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

peptidyl-tyrosine phosphorylation

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

regulation of circadian sleep/wake cycle, sleep

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

histamine secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

cellular response to granulocyte macrophage colony-stimulating factor stimulus

1 reference

8 April 2019

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

regulation of myeloid cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

1 reference

8 April 2019

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

cytokine-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

1 reference

8 April 2019

macrophage differentiation

1 reference

8 April 2019

CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

http://purl.uniprot.org/uniprot/P04141

Gene Atlas image

PBB GE CSF2 210229 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

0 references

Identifiers

1 reference

19 October 2015

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016