(Q41430192)

30 September 2017

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title

Aging and cancer: the double-edged sword of replicative senescence (English)

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30 September 2017

Campisi J

1

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30 September 2017

language of work or name

English

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publication date

1 April 1997

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Journal of the American Geriatrics Society

30 September 2017

published in

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30 September 2017

volume

45

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30 September 2017

issue

4

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30 September 2017

page(s)

482-488

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

30 September 2017

cites work

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Towards an understanding of the malignant transformation of diploid human fibroblasts

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Telomere end-replication problem and cell aging

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Telomeres and telomerase in aging and cancer

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Unusual chromatin in human telomeres

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Structure and function of telomeres

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Telomeres shorten during ageing of human fibroblasts

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Telomere length predicts replicative capacity of human fibroblasts

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Clonal variation in response to adrenocorticotropin in cultured bovine adrenocortical cells: relationship to senescence

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Expression of cell cycle-dependent genes in young and senescent WI-38 fibroblasts

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Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

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Renewed DNA synthesis in senescent WI-38 cells by expression of an inducible chimeric c-fos construct

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Replicative senescence: the human fibroblast comes of age.

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Inhibitors of mammalian G1 cyclin-dependent kinases

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

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Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation

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Senescence stimulates U937-endothelial cell interactions

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Cellular senescence involves stochastic processes causing loss of expression of differentiated function genes: transfection with SV40 as a means for dissociating effects of senescence on growth and on differentiated function gene expression.

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Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity

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Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts

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Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens.

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Senescence as a mode of tumor suppression

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Positional cloning of the Werner's syndrome gene

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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21 January 2018

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21 January 2018

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Interaction between erbB-receptors and heregulin in breast cancer tumor progression and drug resistance

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10.1111/J.1532-5415.1997.TB05175.X

21 January 2018

Identifiers

DOI

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30 September 2017

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