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Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?
scientific article published on July 1996
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scholarly article
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Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
review article
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Europe PubMed Central
title
Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
main subject
neurodegeneration
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author
Thomas Knöpfel
series ordinal
5
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Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Ferdinando Nicoletti
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Valeria Maria Gloria Bruno
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
author name string
Copani A
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Casabona G
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
publication date
1 July 1996
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
published in
Trends in Neurosciences
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
volume
19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
issue
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
page(s)
267-271
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
cites work
Molecular diversity of glutamate receptors and implications for brain function
1 reference
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Crossref
reference URL
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7 January 2021
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Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system
1 reference
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https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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Glutamate neurotoxicity and diseases of the nervous system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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Excitotoxicity and the NMDA receptor--still lethal after eight years
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reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
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Metabotropic glutamate receptors: novel targets for drug development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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NMDA and quisqualate reduce a Ca-dependent K current by a protein kinase-mediated mechanism.
1 reference
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reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: subtype-specific coupling to ion channels
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
L-AP4 inhibits calcium currents and synaptic transmission via a G- protein-coupled glutamate receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabotropic glutamate receptors inhibiting excitatory synapses in the CA1 area of rat hippocampus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Novel agonists for metabotropic glutamate receptors: trans- and cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- and cis-MCG-I)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
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Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the metabotropic glutamate receptor is neuroprotective during nitric oxide toxicity in primary hippocampal neurons of rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
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Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists--an update
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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inferred from DOI database lookup
Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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inferred from DOI database lookup
The expression of two splice variants of metabotropic glutamate receptor subtype 5 in the rat brain and neuronal cells during development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Purkinje cell survival is differentially regulated by metabotropic and ionotropic excitatory amino acid receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inositol trisphosphate and calcium signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Perinatal hypoxic-ischemic brain injury enhances quisqualic acid-stimulated phosphoinositide turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of inositol phospholipid hydrolysis by excitatory amino acids is enhanced in brain slices from vulnerable regions after transient global ischemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C reduces Mg2 block of NMDA-receptor channels as a mechanism of modulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C modulation of NMDA currents: an important link for LTP induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabotropic glutamate receptor antagonist ( )-alpha-methyl-4-carboxyphenylglycine protects hippocampal CA1 neurons of the rat from in vitro hypoxia/hypoglycemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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inferred from DOI database lookup
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
1 reference
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Crossref
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https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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inferred from DOI database lookup
The functional anatomy of basal ganglia disorders
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
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inferred from DOI database lookup
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity of beta-N-methylamino-L-alanine (BMAA) and beta-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between beta-N-methylamino-L-alanine and excitatory amino acid receptors in brain slices and neuronal cultures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pharmacological characterization of the mGluR1α subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of beta-amyloid production by activation of protein kinase C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2 channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016/S0166-2236(96)20019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0166-2236(96)20019-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PubMed publication ID
8799968
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8799968
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799968 AND SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
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