(Q40565443)

21 September 2017

title

The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells (English)

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21 September 2017

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Roxane Engel

1

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21 September 2017

Nikola I Valkov

2

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21 September 2017

Jana L Gump

3

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21 September 2017

Lori Hazlehurst

4

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21 September 2017

William S Dalton

5

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21 September 2017

Daniel M Sullivan

6

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21 September 2017

language of work or name

English

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publication date

1 May 2004

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Experimental Cell Research

21 September 2017

published in

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21 September 2017

volume

295

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21 September 2017

issue

2

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21 September 2017

page(s)

421-431

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DNA topoisomerases: structure, function, and mechanism

21 September 2017

cites work

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Two COOH-terminal truncated cytoplasmic forms of topoisomerase II alpha in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing

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Cell density-dependent VP-16 sensitivity of leukaemic cells is accompanied by the translocation of topoisomerase IIalpha from the nucleus to the cytoplasm

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Topoisomerase II.etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes.

7 January 2021

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Ectopic expression of human topoisomerase IIalpha fragments and etoposide resistance in mammalian cells.

7 January 2021

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Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta

7 January 2021

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Proliferation dependence of topoisomerase II mediated drug action

7 January 2021

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The comet moment as a measure of DNA damage in the comet assay

7 January 2021

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DNA topoisomerase I and II activities during cell proliferation and the cell cycle in cultured mouse embryo fibroblast (C3H 10T1/2) cells

7 January 2021

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Leptomycins A and B, new antifungal antibiotics. III. Mode of action of leptomycin B on Schizosaccharomyces pombe

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Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

7 January 2021

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Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

7 January 2021

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Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells

7 January 2021

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Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase IIα associated with nuclear matrices from wild-type and drug-resistant Chinese hamster ovary cell lines

7 January 2021

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The cytochrome b5 tail anchors and stabilizes subdomains of human DNA topoisomerase II alpha in the cytoplasm of retrovirally infected mammalian cells.

7 January 2021

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10.1016/J.YEXCR.2004.01.012

7 January 2021

Identifiers

DOI

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21 September 2017

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