(Q40511940)

English

Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia

scientific article published on December 1990

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia (English)

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

author name string

Tracey KJ

1

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Morgello S

2

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Koplin B

3

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Fahey TJ 3rd

4

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Fox J

5

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Aledo A

6

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Manogue KR

7

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Cerami A

8

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

language of work or name

0 references

publication date

1 December 1990

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

86

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

2014-2024

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Starvation in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Acquired hypertrichosis lanuginosa and malignancy. A clinical review and histopathologic evaluation with special attention to the "mantle" hair of Pinkus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Nutrition and cancer: physiological interrelationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Shock and tissue injury induced by recombinant human cachectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

General metabolic abnormalities in cancer patients: anorexia and cachexia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-alpha in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Recombinant human tumor necrosis factor induces acute reductions in food intake and body weight in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Interleukin 1, tumour necrosis factor-alpha (cachectin) and the pathogenesis of cancer cachexia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Tolerance to tumor necrosis factor in rats and the relationship to endotoxin tolerance and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Tumor necrosis factor and the acute metabolic response to tissue injury in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

The neurobiology of human immunodeficiency virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Interleukin-1-induced anorexia in the rat. Influence of prostaglandins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Cachectin/tumour necrosis factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Metabolic responses to cachectin/TNF. A brief review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Acquired hypertrichosis lanuginosa.Report of two new cases and a review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

22 September 2017

Correlation of interleukin-1 beta and cachectin concentrations in cerebrospinal fluid and outcome from bacterial meningitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

25 September 2017

Specific loss of the hypoglycemic control of feeding in recovered lateral rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Tumors secreting human TNF/cachectin induce cachexia in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Interleukin 1 and tumor necrosis factor do not regulate protein balance in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Interleukin 1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Raised serum levels of tumour necrosis factor in parasitic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Detection of circulating tumor necrosis factor after endotoxin administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Cachectin/tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Reversal of weight loss induced by tumour necrosis factor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Characterization of tumor necrosis factor-alpha receptors in human and rat thyroid cells and regulation of the receptors by thyrotropin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Impairment of hypothalamic-pituitary-thyroid function in rats treated with human recombinant tumor necrosis factor-alpha (cachectin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Origins of nutritional imbalance in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

Control of food intake in cancer cachexia: a challenge and a tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

17 June 2018

The effect of interleukin-2 on the blood-brain barrier in the 9L gliosarcoma rat model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

3 July 2018

Regulation of food intake and hepatic protein synthesis by recombinant-derived cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329839

20 August 2018

Cancer cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncomplicated starvation versus cancer cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism by which uptake inhibitors antagonize p-chloroamphetamine-induced depletion of brain serotonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer cachexia and protein metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cachectin/tumour-necrosis-factor production by cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein and substrate metabolism during starvation and parenteral refeeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor Necrosis Factor Not Detectable in Patients With Clinical Cancer Cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor and interleukin-1 beta: suppression of food intake by direct action in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cachectin activity in the serum of cachectic, tumor-bearing rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticachectin/tumor necrosis factor-alpha antibodies attenuate development of cachexia in tumor models

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of the toxic effects of cachectin by concurrent insulin administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure to tumor necrosis factor in vivo preferentially inhibits erythropoiesis in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A stimulates hair growth in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EVIDENCE FOR TUMOUR NECROSIS FACTOR/CACHECTIN PRODUCTION IN CANCER

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine appearance in human endotoxemia and primate bacteremia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2254457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI114937

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

ResearchGate publication ID

0 references

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