(Q40299850)

English

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

scientific article published on 24 March 2006

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

0 references

Peter J. Ratcliffe

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Jonathan M. Gleadle

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Gareth P Elvidge

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Louisa Glenny

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Rebecca J Appelhoff

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Jiannis Ragoussis

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

0 references

publication date

24 March 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

281

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

15215-15226

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1093/NAR/30.9.E36

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

A novel quasi-viral agent, MaTu, is a two-component system

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Targeting HIF-1 for cancer therapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group (HMG) box 9].

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Activation of the interferon system by short-interfering RNAs

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Targeted replacement of hypoxia-inducible factor-1alpha by a hypoxia-inducible factor-2alpha knock-in allele promotes tumor growth

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Human HIF-3alpha4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

How oxygen makes its presence felt

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Oxygen sensing by HIF hydroxylases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Development and evaluation of real competitive PCR for high-throughput quantitative applications

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The serine/threonine kinase Pim-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Inhibition of prolyl 4-hydroxylase by oxalyl amino acid derivatives in vitro, in isolated microsomes and in embryonic chicken tissues

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

The genomic response of tumor cells to hypoxia and reoxygenation. Differential activation of transcription factors AP-1 and NF-kappa B

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M511408200

Identifiers

10.1074/JBC.M511408200

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40299850&oldid=1894198379"