(Q40022750)

English

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

scientific article published on July 1997

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

author name string

V S Shapiro

1

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

K E Truitt

2

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

J B Imboden

3

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

A Weiss

4

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

4051-4058

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Signal transduction by lymphocyte antigen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Transcriptional regulation of the IL-2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

The ups and downs of T cell costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

The B7 and CD28 receptor families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Adhesion receptors of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Analysis of the AP-1 sites in the IL-2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Regulation of the interleukin-2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

22 September 2017

Molecular regulation of the IL-2 gene: rheostatic control of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

25 September 2017

An enhanced immune response in mice lacking the transcription factor NFAT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

25 September 2017

Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells. Convergence of costimulatory signals and differences from transformed T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

25 September 2017

Activation of IL-2 receptor alpha-chain gene by individual members of the rel oncogene family in association with serum response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

25 September 2017

c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

17 June 2018

Transactivation by AP-1 is a molecular target of T cell clonal anergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

17 June 2018

Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

17 June 2018

Structural requirements for CD28-mediated costimulation of IL-2 production in Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

20 August 2018

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

20 August 2018

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232258

20 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9199340

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9199340

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear appearance of a factor that binds the CD28 response element within the interleukin-2 enhancer correlates with interleukin-2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/9199340

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9199340

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/9199340

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.17.7.4051

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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