(Q39827761)

15 September 2017

title

Ethyl pyruvate administration inhibits hepatic tumor growth (English)

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6

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7

Herbert J Zeh

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9

Michael T Lotze

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15 September 2017

Xiaoyan Liang

1

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15 September 2017

Antonio Romo de Vivar Chavez

2

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Nicole E Schapiro

3

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Patricia Loughran

4

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Stephen H Thorne

5

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Donna Beer-Stolz

8

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Michael E de Vera

10

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15 September 2017

publication date

1 September 2009

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Journal of Leukocyte Biology

15 September 2017

published in

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15 September 2017

volume

86

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15 September 2017

issue

3

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15 September 2017

page(s)

599-607

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15 September 2017

cites work

Cancer statistics, 2008

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A poly(dA-dT) upstream activating sequence binds high-mobility group I protein and contributes to lymphotoxin (tumor necrosis factor-beta) gene regulation

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Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype

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RAGE signaling sustains inflammation and promotes tumor development

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High mobility group box I (HMGB1) release from tumor cells after treatment: implications for development of targeted chemoimmunotherapy

21 January 2018

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Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF-kappaB pathway

21 January 2018

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Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers

21 January 2018

1 reference

Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation

21 January 2018

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Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosis

21 January 2018

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Ethyl pyruvate improves survival and ameliorates distant organ injury in rats with severe acute pancreatitis

21 January 2018

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Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.

21 January 2018

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Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas

21 January 2018

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The selectivity of autophagy and its role in cell death and survival

21 January 2018

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Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

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Immune cells as mediators of solid tumor metastasis

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin

21 January 2018

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HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling

21 January 2018

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HMG-1 as a late mediator of endotoxin lethality in mice

21 January 2018

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Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors.

21 January 2018

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The paradox of autophagy and its implication in cancer etiology and therapy

21 January 2018

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Guanine nucleotide exchange on heterotrimeric Gi3 protein controls autophagic sequestration in HT-29 cells.

21 January 2018

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

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A phase II multicenter double-blind placebo-controlled study of ethyl pyruvate in high-risk patients undergoing cardiac surgery with cardiopulmonary bypass

21 January 2018

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The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.

21 January 2018

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Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1189/JLB.0908578

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15 September 2017

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