(Q37854912)

24 August 2017

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title

Autophagic pathways in Parkinson disease and related disorders (English)

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24 August 2017

0 references

1 reference

Maria Xilouri

1

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24 August 2017

Leonidas Stefanis

series ordinal

2

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24 August 2017

language of work or name

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21 March 2011

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Expert Reviews in Molecular Medicine

24 August 2017

published in

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24 August 2017

volume

13

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24 August 2017

page(s)

e8

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The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

24 August 2017

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Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

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21 January 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

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21 January 2018

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21 January 2018

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

21 January 2018

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Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

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A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

21 January 2018

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Bcl-2 family members: dual regulators of apoptosis and autophagy

21 January 2018

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Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51

21 January 2018

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Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

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Atg101, a novel mammalian autophagy protein interacting with Atg13

21 January 2018

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Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy

21 January 2018

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Regulation mechanisms and signaling pathways of autophagy

21 January 2018

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Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

mTOR regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

The molecular machinery of autophagy: unanswered questions

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Chaperone-mediated autophagy markers in Parkinson disease brains

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Consequences of the selective blockage of chaperone-mediated autophagy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Identification of regulators of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Peptide sequences that target cytosolic proteins for lysosomal proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

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Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein

21 January 2018

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Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

21 January 2018

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Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

The origin of the autophagosomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

21 January 2018

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The pleiotropic role of autophagy: from protein metabolism to bactericide.

21 January 2018

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Autophagy in health and disease: a double-edged sword

21 January 2018

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Autophagic tubes: vacuolar invaginations involved in lateral membrane sorting and inverse vesicle budding

21 January 2018

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21 January 2018

Functions of lysosomes

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Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Pathogenic lysosomal depletion in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Ultrastructure of Lewy bodies in the stellate ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Autophagy and neurodegeneration: when the cleaning crew goes on strike

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Regulation of lamp2a levels in the lysosomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

A receptor for the selective uptake and degradation of proteins by lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Autophagy genes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Autophagy and aging: the importance of maintaining "clean" cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Methods for monitoring autophagy using GFP-LC3 transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Autophagosomes in GFP-LC3 Transgenic Mice

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Methods for monitoring autophagy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Induction of macroautophagy by overexpression of the Parkinson's disease-associated GPR37 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Cell death pathways in Parkinson's disease: role of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Genes necessary for directed axonal elongation or fasciculation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Molecular pathogenesis of Parkinson disease: insights from genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Parkinson's disease: mechanisms and models

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Protein aggregation and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

α-Synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Parkinson disease, LRRK2 and the endocytic-autophagic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Lysosomal degradation of alpha-synuclein in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

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https://api.crossref.org/works/10.1017/S1462399411001803

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Nix is a selective autophagy receptor for mitochondrial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

Endocytosis and autophagy in dying neurons: an ultrastructural study in chick embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Methods in mammalian autophagy research

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Degradation of alpha-synuclein by proteasome

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Neuropathology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

alpha-synuclein degradation by autophagic pathways: a potential key to Parkinson's disease pathogenesis.

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Ambra1 regulates autophagy and development of the nervous system

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Eaten alive: a history of macroautophagy

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Protein degradation in the aging organism.

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

1 reference

https://api.crossref.org/works/10.1017/S1462399411001803

7 January 2021

10.1017/S1462399411001803

Identifiers

DOI

1 reference

24 August 2017

1 reference