(Q37372729)

English

Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors

scientific article published on September 15, 1997

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Europe PubMed Central

PMC publication ID

20 August 2017

Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors (English)

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Europe PubMed Central

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20 August 2017

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Fauci AS

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20 August 2017

Giuseppe Pantaleo

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Pantaleo G

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Europe PubMed Central

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20 August 2017

Joseph B Margolick

24

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Margolick JB

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20 August 2017

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Davey RT Jr

14

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Europe PubMed Central

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20 August 2017

O. J. Cohen

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

M. Vaccarezza

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

G. K. Lam

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15 November 2024

B. F. Baird

4

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Europe PubMed Central

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15 November 2024

K. Wildt

5

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Europe PubMed Central

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15 November 2024

P. M. Murphy

6

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Europe PubMed Central

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15 November 2024

P. A. Zimmerman

7

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Europe PubMed Central

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15 November 2024

T. B. Nutman

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

C. H. Fox

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Europe PubMed Central

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15 November 2024

S. Hoover

10

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Europe PubMed Central

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15 November 2024

J. Adelsberger

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Europe PubMed Central

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15 November 2024

M. Baseler

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

J. Arthos

13

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

R. T. Davey

14

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

R. L. Dewar

15

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

J. Metcalf

16

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Europe PubMed Central

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15 November 2024

D. J. Schwartzentruber

17

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

J. M. Orenstein

18

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Europe PubMed Central

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15 November 2024

S. Buchbinder

19

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Europe PubMed Central

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15 November 2024

A. J. Saah

20

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Europe PubMed Central

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15 November 2024

R. Detels

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Europe PubMed Central

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15 November 2024

J. Phair

22

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Europe PubMed Central

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15 November 2024

C. Rinaldo

23

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Europe PubMed Central

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15 November 2024

A. S. Fauci

26

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Europe PubMed Central

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15 November 2024

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publication date

1 September 1997

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20 August 2017

15 September 1997

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9294127

15 November 2024

number of pages

9

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full work available at URL

http://www.jci.org/articles/view/119682/files/pdf

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

https://europepmc.org/articles/PMC508340

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

https://europepmc.org/articles/PMC508340?pdf=render

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9294127

15 November 2024

http://www.jci.org/articles/view/119682/files/pdf

1 reference

10.1172/JCI119682

https://api.crossref.org/works/10.1172/JCI119682

15 November 2024

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

100

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1581-1589

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

CD8 T-cell-derived soluble factor(s), but not beta-chemokines RANTES, MIP-1 alpha, and MIP-1 beta, suppress HIV-1 replication in monocyte/macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Host factors and the pathogenesis of HIV-induced disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

HIV replication in CD4 T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous beta-chemokines and the viral inductive effects of other endogenous cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

HIV-1 entry into CD4 cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Non-progression in HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. Multicenter Hemophilia Cohort and Hemophilia Growth and Development Studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects downregulation of viral replication in lymphoid tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

6 September 2017

Lymphoid organs function as major reservoirs for human immunodeficiency virus

1 reference

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14 September 2017

Metabolic polymorphisms and cancer susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Host genetics and infectious disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Multifactorial nature of human immunodeficiency virus disease: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Splicing variability in HIV type 1 revealed by quantitative RNA polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

28 September 2017

Antigenic oscillations and shifting immunodominance in HIV-1 infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

26 June 2018

Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

26 June 2018

Comparable biological and molecular determinants in HIV type 1-infected long-term nonprogressors and recently infected individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

The characterization of non-progressors: long-term HIV-1 infection with stable CD4 T-cell levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Studies in subjects with long-term nonprogressive human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Long-Term Human Immunodeficiency Virus Infection in Asymptomatic Homosexual and Bisexual Men with Normal CD4 Lymphocyte Counts: Immunologic and Virologic Characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508340

2 September 2018

Identification of multiple and distinct CD8 T cell suppressor activities: dichotomy between infected and uninfected individuals, evolution with progression of disease, and sensitivity to gamma irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and epidemiologic features of primary HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 infection in an individual homozygous for the CCR5 deletion allele

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 infection in a man homozygous for CCR5▵32

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/9294127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119682

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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