(Q37333331)

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Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

scientific article published on 29 June 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts (English)

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19 August 2017

Clostridium difficile

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Julian Parkhill

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19 August 2017

Richard Stabler

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Richard A Stabler

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Alan W Walker

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12

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Brendan W Wren

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19 August 2017

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14

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Gordon Dougan

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19 August 2017

Nicholas J Croucher

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Nicholas Croucher

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19 August 2017

2

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Simon Clare

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19 August 2017

1

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Trevor D Lawley

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19 August 2017

Neil F Fairweather

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Neil F Fairweather

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19 August 2017

Piero Mastroeni

7

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Piero Mastroeni

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19 August 2017

9

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Claire Raisen

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19 August 2017

10

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Lynda Mottram

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David Goulding

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19 August 2017

Paul Scott

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19 August 2017

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publication date

29 June 2009

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19 August 2017

Infection and Immunity

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19 August 2017

77

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Europe PubMed Central

PMC publication ID

19 August 2017

9

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Europe PubMed Central

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19 August 2017

3661-3669

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737984

6 September 2017

Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation

1 reference

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6 September 2017

Toxin B is essential for virulence of Clostridium difficile

1 reference

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Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

1 reference

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6 September 2017

The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing

1 reference

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6 September 2017

Clostridium difficile--more difficult than ever

1 reference

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6 September 2017

A mouse model of Clostridium difficile-associated disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737984

6 September 2017

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

1 reference

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6 September 2017

Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection

1 reference

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6 September 2017

Evolution of mammals and their gut microbes

1 reference

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6 September 2017

Clostridium difficile: from obscurity to superbug

1 reference

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6 September 2017

Infection control measures to limit the spread of Clostridium difficile

1 reference

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6 September 2017

The role of microbiota in infectious disease

1 reference

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6 September 2017

The myeloid differentiation factor 88 (MyD88) is required for CD4 T cell effector function in a murine model of inflammatory bowel disease.

1 reference

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6 September 2017

Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea

1 reference

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6 September 2017

Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota

1 reference

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6 September 2017

Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents

1 reference

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6 September 2017

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

1 reference

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6 September 2017

Unravelling the pathogenesis of inflammatory bowel disease

1 reference

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6 September 2017

Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737984

6 September 2017

Narrative review: the new epidemic of Clostridium difficile-associated enteric disease

1 reference

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6 September 2017

Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains

1 reference

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6 September 2017

In vivo bioluminescence imaging of the murine pathogen Citrobacter rodentium

1 reference

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6 September 2017

Construction and analysis of chromosomal Clostridium difficile mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737984

6 September 2017

Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB

1 reference

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6 September 2017

Clostridium difficile: an important pathogen of food animals

1 reference

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6 September 2017

Modelling infectious disease - time to think outside the box?

1 reference

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6 September 2017

Superspreading and the effect of individual variation on disease emergence

1 reference

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6 September 2017

A comparative genomic view of clostridial sporulation and physiology

1 reference

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6 September 2017

Diversity of the human intestinal microbial flora

1 reference

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6 September 2017

Clostridium difficile causing acute renal failure: case presentation and review.

1 reference

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6 September 2017

Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness

1 reference

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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

1 reference

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6 September 2017

Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host

1 reference

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Host-induced epidemic spread of the cholera bacterium

1 reference

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6 September 2017

Clinical practice. Antibiotic-associated diarrhea

1 reference

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6 September 2017

Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients

1 reference

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6 September 2017

Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A.

1 reference

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

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Heterogeneities in the transmission of infectious agents: implications for the design of control programs

1 reference

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6 September 2017

Use of sodium taurocholate to enhance spore recovery on a medium selective for Clostridium difficile.

1 reference

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Comparison of alcohol shock enrichment and selective enrichment for the isolation of Clostridium difficile

1 reference

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6 September 2017

Relationship between levels of Clostridium difficile toxin A and toxin B and cecal lesions in gnotobiotic mice

1 reference

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Interaction of enteric bacterial pathogens with murine embryonic stem cells

1 reference

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Colonization resistance

1 reference

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Efficiency of various bile salt preparations for stimulation of Clostridium difficile spore germination.

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Clostridium difficile in gnotobiotic mice

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Molecular genetics of sporulation in Bacillus subtilis.

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Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078.

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Mortality of patients with antibiotic-associated diarrhoea: the impact of Clostridium difficile

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Infection of hamsters with historical and epidemic BI types of Clostridium difficile

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Long-term ecological impacts of antibiotic administration on the human intestinal microbiota

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Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice

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Efficacy of hospital cleaning agents and germicides against epidemic Clostridium difficile strains.

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Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease?

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Clostridium difficile and acute respiratory distress syndrome

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Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome

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Pathogenesis of Clostridium difficile infection

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2 September 2018

The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses.

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2 September 2018

The ClosTron: a universal gene knock-out system for the genus Clostridium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19564382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clostridium difficile infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19564382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clostridium difficile colonization in healthy adults: transient colonization and correlation with enterococcal colonization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19564382

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.00558-09

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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