(Q37328463)

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The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling

scientific article published on 24 August 2009

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19726885 AND SRC:MED&resulttype=core&format=json

6 February 2020

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling (English)

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6 February 2020

J Chuck Harrell

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6 February 2020

Ricardo D Coletta

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Ricardo D Coletta

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6 February 2020

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Douglas S Micalizzi

1

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6 February 2020

Kimberly L Christensen

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6 February 2020

Paul Jedlicka

3

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6 February 2020

Anna E Barón

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6 February 2020

Kathryn B Horwitz

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6 February 2020

Dean Billheimer

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6 February 2020

Karen A Heichman

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6 February 2020

Alana L Welm

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6 February 2020

William P Schiemann

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6 February 2020

Heide L Ford

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6 February 2020

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24 August 2009

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6 February 2020

Journal of Clinical Investigation

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6 February 2020

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6 February 2020

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6 February 2020

2678-2690

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6 February 2020

ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells

1 reference

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6 September 2017

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

1 reference

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Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium

1 reference

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6 September 2017

Modelling breast cancer: one size does not fit all.

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

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6 September 2017

Role of transforming growth factor-beta in cancer progression

1 reference

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Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

1 reference

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1 reference

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Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma

1 reference

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6 September 2017

Breast cancer-derived factors facilitate osteolytic bone metastasis.

1 reference

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ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells

1 reference

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6 September 2017

Transforming growth factor-beta in cancer and metastasis

1 reference

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Tumor metastasis: mechanistic insights and clinical challenges

1 reference

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6 September 2017

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

1 reference

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6 September 2017

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1 reference

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Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

1 reference

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6 September 2017

Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

1 reference

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6 September 2017

Homeobox gene expression in cancer: insights from developmental regulation and deregulation

1 reference

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6 September 2017

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

1 reference

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6 September 2017

TGF-beta and epithelial-to-mesenchymal transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

Molecular requirements for epithelial-mesenchymal transition during tumor progression

1 reference

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6 September 2017

A molecular classification of papillary renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

ONCOMINE: a cancer microarray database and integrated data-mining platform

1 reference

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6 September 2017

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

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6 September 2017

Classification and subtype prediction of adult soft tissue sarcoma by functional genomics

1 reference

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6 September 2017

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

Six1 is required for the early organogenesis of mammalian kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

Altered myogenesis in Six1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2735914

6 September 2017

A gene-expression signature as a predictor of survival in breast cancer

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6 September 2017

Deregulated homeobox gene expression in cancer: cause or consequence?

1 reference

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6 September 2017

Epithelial-mesenchymal transitions in tumour progression

1 reference

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Beta-catenin is essential and sufficient for skeletal myogenesis in P19 cells

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1 reference

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Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein

1 reference

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Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis

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Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol

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Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.

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Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells

1 reference

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1 reference

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Gene amplification is a mechanism of Six1 overexpression in breast cancer

1 reference

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TGF-beta in mammary gland development and breast cancer.

1 reference

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1 reference

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Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation

1 reference

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1 reference

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1 reference

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2 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A window on the dynamics of biological switches

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https://pubmed.ncbi.nlm.nih.gov/19726885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI37815

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19726885 AND SRC:MED&resulttype=core&format=json

6 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19726885 AND SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19726885 AND SRC:MED&resulttype=core&format=json

6 February 2020

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