(Q37040069)

English

TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite

scientific article published on September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Toxoplasma gondii

0 references

toll-like receptor

0 references

1 reference

based on heuristic

inferred from title

author name string

Woraporn Sukhumavasi

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Charlotte E Egan

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Amy L Warren

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Gregory A Taylor

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Barbara A Fox

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

David J Bzik

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Eric Y Denkers

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

1 September 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

181

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

3464-3473

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

T cell expression of MyD88 is required for resistance to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Understanding the multiple functions of Gr-1( ) cell subpopulations during microbial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

MyDths and un-TOLLed truths: sensor, instructive and effector immunity to tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Toll-Like receptors (TLRs) and their ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Recognition of microorganisms and activation of the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Cooperation of Toll-like receptor signals in innate immune defence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Innate immunity--cross-talk with adaptive immunity through pattern recognition receptors and cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Toll-like receptor recognition of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Involvement of intestinal dendritic cells in oral tolerance, immunity to pathogens, and inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Polymorphonuclear neutrophils improve replication of Chlamydia pneumoniae in vivo upon MyD88-dependent attraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

29 September 2017

MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

27 June 2018

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

27 June 2018

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

MyD88 is required for the formation of long-term humoral immunity to virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Dissemination of Toxoplasma gondii to immunoprivileged organs and role of Toll/interleukin-1 receptor signalling for host resistance assessed by in vivo bioluminescence imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Toll-dependent control mechanisms of CD4 T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Protective T cell response against intracellular pathogens in the absence of Toll-like receptor signaling via myeloid differentiation factor 88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

In the absence of IL-12, CD4( ) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 September 2018

Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614926

4 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Protective Cell-Mediated Immunity to Listeria monocytogenes in the Absence of Myeloid Differentiation Factor 88

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel population of Gr-1 -activated macrophages induced during acute toxoplasmosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MyD88 plays a unique role in host defense but not arthritis development in Lyme disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-gamma-independent IL-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4 T cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immune activation and CD4 T cell priming during respiratory fungal infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors control activation of adaptive immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18714019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.181.5.3464

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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