(Q36266461)

13 August 2017

title

Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond (English)

1 reference

13 August 2017

2

Hidde L Ploegh

1 reference

13 August 2017

Brendan N Lilley

1

1 reference

13 August 2017

language of work or name

1 reference

1 October 2005

1 reference

13 August 2017

published in

Immunological Reviews

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13 August 2017

volume

207

1 reference

13 August 2017

page(s)

126-144

1 reference

Viral subversion of the immune system

13 August 2017

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A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes

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The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues

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The human cytomegalovirus gene product US6 inhibits ATP binding by TAP

21 January 2018

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Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP).

21 January 2018

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Bovine herpesvirus 1 interferes with TAP-dependent peptide transport and intracellular trafficking of MHC class I molecules in human cells.

21 January 2018

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An early pseudorabies virus protein down-regulates porcine MHC class I expression by inhibition of transporter associated with antigen processing (TAP).

21 January 2018

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Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

21 January 2018

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Human cytomegalovirus inhibits antigen presentation by a sequential multistep process

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains

21 January 2018

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Structural and functional dissection of human cytomegalovirus US3 in binding major histocompatibility complex class I molecules

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Determinant for endoplasmic reticulum retention in the luminal domain of the human cytomegalovirus US3 glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus immediate early glycoprotein US3 retains MHC class I molecules by transient association

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus inhibits tapasin-dependent peptide loading and optimization of the MHC class I peptide cargo for immune evasion

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The luminal part of the murine cytomegalovirus glycoprotein gp40 catalyzes the retention of MHC class I molecules

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

MHC class I ubiquitination by a viral PHD/LAP finger protein.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Virus subversion of the MHC class I peptide-loading complex

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Viral degradation of the MHC class I peptide loading complex

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4 T lymphocytes.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Epstein-Barr virus gp42 is posttranslationally modified to produce soluble gp42 that mediates HLA class II immune evasion.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Binding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus US2 causes similar effects on both major histocompatibility complex class I and II proteins in epithelial and glial cells

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Inhibition of HLA-DR assembly, transport, and loading by human cytomegalovirus glycoprotein US3: a novel mechanism for evading major histocompatibility complex class II antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

ARF1 regulates Nef-induced CD4 degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A role for N-glycanase in the cytosolic turnover of glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

US2, a Human Cytomegalovirus-encoded Type I Membrane Protein, Contains a Non-cleavable Amino-terminal Signal Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Trophoblast class I major histocompatibility complex (MHC) products are resistant to rapid degradation imposed by the human cytomegalovirus (HCMV) gene products US2 and US11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Human cytomegalovirus US3 chimeras containing US2 cytosolic residues acquire major histocompatibility class I and II protein degradation properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The HCMV gene products US11 and US2 differ in their ability to attack allelic forms of murine major histocompatibility complex (MHC) class I heavy chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Amino acid composition of alpha1/alpha2 domains and cytoplasmic tail of MHC class I molecules determine their susceptibility to human cytomegalovirus US11-mediated down-regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Helical membrane protein folding, stability, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Endoplasmic reticulum-associated protein degradation--one model fits all?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Quality control in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Endoplasmic reticulum-associated degradation: exceptions to the rule

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Quantitating protein synthesis, degradation, and endogenous antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The putative natural killer decoy early gene m04 (gp34) of murine cytomegalovirus encodes an antigenic peptide recognized by protective antiviral CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Checkpoints in ER-associated degradation: excuse me, which way to the proteasome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Processing of N-linked glycans during endoplasmic-reticulum-associated degradation of a short-lived variant of ribophorin I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates: roles of endoplamic reticulum-bound p97/Cdc48p and proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The engagement of Sec61p in the ER dislocation process

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Ubiquitination Is Required for the Retro-translocation of a Short-lived Luminal Endoplasmic Reticulum Glycoprotein to the Cytosol for Degradation by the Proteasome

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Structural insight into the protein translocation channel

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Membrane protein degradation by AAA proteases in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Reconstitution of membrane proteolysis by FtsH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Retrotranslocation of MHC class I heavy chain from the endoplasmic reticulum to the cytosol is dependent on ATP supply to the ER lumen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A cryptic protease couples deubiquitination and degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Multiple associated proteins regulate proteasome structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Der3p/Hrd1p Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Lumenal and Integral Membrane Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The role of multiubiquitination in dislocation and degradation of the alpha subunit of the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Nucleotide dependent motion and mechanism of action of p97/VCP

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Yeast N-glycanase distinguishes between native and non-native glycoproteins

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Intracellular targeting of the proteasome

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

21 January 2018

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Integral UBL domain proteins: a family of proteasome interacting proteins.

21 January 2018

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https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

Characterization of mammalian selenoproteomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

How do cytotoxic lymphocytes kill their targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00318.X

10.1111/J.0105-2896.2005.00318.X

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference