(Q36108977)

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Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected mice

scientific article published on September 8, 2010

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Europe PubMed Central

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12 August 2017

Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected mice (English)

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12 August 2017

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phenylbutyric acid

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5 July 2024

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Wenhui Hu

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Xianghong Kuang

1

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12 August 2017

Mingshan Yan

3

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12 August 2017

Paul K. Y. Wong

4

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8 September 2010

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12 August 2017

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20813146/pdf/?tool=EBI

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https://europepmc.org/articles/PMC3402222

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https://europepmc.org/articles/PMC3402222?pdf=render

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5 July 2024

https://doi.org/10.1016/j.neuint.2010.08.010

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https://api.elsevier.com/content/article/PII:S0197018610002652?httpAccept=text/xml

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10.1016/J.NEUINT.2010.08.010

https://api.crossref.org/works/10.1016/J.NEUINT.2010.08.010

5 July 2024

https://api.elsevier.com/content/article/PII:S0197018610002652?httpAccept=text/plain

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10.1016/J.NEUINT.2010.08.010

https://api.crossref.org/works/10.1016/J.NEUINT.2010.08.010

5 July 2024

Neurochemistry International

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Europe PubMed Central

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12 August 2017

57

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Europe PubMed Central

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12 August 2017

7

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Europe PubMed Central

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12 August 2017

738-748

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Endoplasmic reticulum stress and atherosclerosis

1 reference

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1 reference

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1 reference

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1 reference

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Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress

1 reference

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Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase

1 reference

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The degree of folding instability of the envelope protein of a neurovirulent murine retrovirus correlates with the severity of the neurological disease

1 reference

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Protein misfolding and aggregation in Parkinson's disease.

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Endoplasmic reticulum protein quality control in neurodegenerative disease: the good, the bad and the therapy

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ER stress and unfolded protein response in amyotrophic lateral sclerosis

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The drug monosodium luminol (GVT) preserves thymic epithelial cell cytoarchitecture and allows thymocyte survival in mice infected with the T cell-tropic, cytopathic retrovirus ts1.

1 reference

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

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Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

1 reference

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The endoplasmic reticulum stress response in immunity and autoimmunity

1 reference

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2 October 2017

Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivo

1 reference

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2 October 2017

From endoplasmic-reticulum stress to the inflammatory response

1 reference

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2 October 2017

The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration

1 reference

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2 October 2017

Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress

1 reference

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Adapting proteostasis for disease intervention

1 reference

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2 October 2017

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

2 October 2017

Expression of murine leukemia virus envelope protein is sufficient for the induction of apoptosis

1 reference

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2 October 2017

The endoplasmic reticulum and the unfolded protein response

1 reference

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2 October 2017

The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

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Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

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ER chaperones in mammalian development and human diseases

1 reference

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2 October 2017

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

2 October 2017

Retrovirus-induced oxidative stress with neuroimmunodegeneration is suppressed by antioxidant treatment with a refined monosodium alpha-luminol (Galavit).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

2 October 2017

Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

2 October 2017

Astrocytes survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus Moloney murine leukemia virus by upregulation of antioxidant defenses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402222

2 October 2017

Stressing out the ER: a role of the unfolded protein response in prion-related disorders

1 reference

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ER stress and neurodegenerative diseases

1 reference

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Cellular response to endoplasmic reticulum stress: a matter of life or death

1 reference

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Synthesis, assembly, and processing of the Env ERVWE1/syncytin human endogenous retroviral envelope

1 reference

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Control of Atm-/- thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone

1 reference

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1 reference

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Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes

1 reference

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Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination

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Molecular mechanisms of neurotoxicity of pathological prion protein

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1 reference

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1 reference

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Endogenous retroviruses in the human genome sequence

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1 reference

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1 reference

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Initial sequencing and analysis of the human genome

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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Control of ER stress by a chemical chaperone counteracts apoptotic signals in IFN-gamma-treated murine hepatocytes

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Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model

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Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.

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Protein disulfide isomerase is cleaved by caspase-3 and -7 during apoptosis.

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The unfolded protein response affects neuronal cell cycle protein expression: implications for Alzheimer's disease pathogenesis

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Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes

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23 September 2018

Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy

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Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes

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The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death

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Induction of p53 accumulation by Moloney murine leukemia virus-ts1 infection in astrocytes via activation of extracellular signal-regulated kinases 1/2.

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Motor neuronal loss and neurofilament-ubiquitin alteration in MoMuLV-ts1 encephalopathy

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Neurodegeneration induced by MoMuLV-ts1 and increased expression of Fas and TNF-alpha in the central nervous system

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Development of pathological lesions in the central nervous system of transgenic mice expressing theenvgene oftS1 Moloney murine leukemia virus in the absence of the viralgagandpolgenes and viral replication

1 reference

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Murine leukemia virus induced central nervous system diseases

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23 September 2018

Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the endoplasmic reticulum stress response marker, BiP, in the central nervous system of HIV-positive individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein disulfide isomerase is both an enzyme and a chaperone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20813146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUINT.2010.08.010

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

release_xtx7qbzbrfc3tca7pgnmwi2ps4

1 reference

https://api.fatcat.wiki/v0/release/xtx7qbzbrfc3tca7pgnmwi2ps4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

Sitelinks

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