(Q36052460)

11 August 2017

Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: in vitro and in vivo studies (English)

1 reference

11 August 2017

S Agrawal

1

1 reference

11 August 2017

Z Jiang

2

1 reference

11 August 2017

Q Zhao

3

1 reference

11 August 2017

D Shaw

4

1 reference

11 August 2017

Q Cai

5

1 reference

11 August 2017

A Roskey

6

1 reference

11 August 2017

L Channavajjala

7

1 reference

11 August 2017

C Saxinger

8

1 reference

11 August 2017

R Zhang

9

1 reference

11 August 2017

language of work or name

English

0 references

publication date

1 March 1997

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

94

1 reference

11 August 2017

6

1 reference

11 August 2017

2620-2625

1 reference

Antisense oligonucleotides: towards clinical trials

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Antisense oligodeoxynucleotide phosphorothioate complementary to Gag mRNA blocks replication of human immunodeficiency virus type 1 in human peripheral blood cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

In vivo toxicological effects of rel A antisense phosphorothioates in CD-1 mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

CpG motifs in bacterial DNA trigger direct B-cell activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20138

Large-scale synthesis, purification, and analysis of oligodeoxynucleotide phosphorothioates

11 July 2018

1 reference

12 December 2020

In vivo stability, disposition and metabolism of a “hybrid” oligonucleotide phosphorothioate in rats

1 reference

12 December 2020

Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration

1 reference

12 December 2020

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

1 reference

12 December 2020

Novel enzymatic and immunological responses to oligonucleotides

1 reference

12 December 2020

Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleoside phosphorothioate in rats after intravenous administration

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.6.2620

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

9122245

1 reference