(Q35590351)

9 August 2017

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title

Pharmacogenetics goes genomic (English)

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9 August 2017

David B Goldstein

1

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9 August 2017

Sarah K Tate

series ordinal

2

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9 August 2017

Sanjay M Sisodiya

series ordinal

3

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9 August 2017

publication date

1 December 2003

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9 August 2017

published in

Nature Reviews Genetics

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9 August 2017

volume

4

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9 August 2017

issue

12

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9 August 2017

page(s)

937-947

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Drug reactions enzymes, and biochemical genetics

9 August 2017

cites work

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Polymorphic hydroxylation of Debrisoquine in man.

21 January 2018

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The evolution of drug metabolism

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Pharmacogenomics: translating functional genomics into rational therapeutics

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Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

21 January 2018

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beta-2 Adrenergic receptor variants affect resting blood pressure and agonist-induced vasodilation in young adult Caucasians

21 January 2018

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The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization

21 January 2018

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Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

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Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure

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Pharmacogenetics of Asthma

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A comprehensive review of genetic association studies

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Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

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Multidrug resistance in cancer: role of ATP-dependent transporters

21 January 2018

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Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data

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Use of unlinked genetic markers to detect population stratification in association studies.

21 January 2018

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Detecting association in a case-control study while correcting for population stratification

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Neuregulin 1 and susceptibility to schizophrenia

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Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

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High-resolution haplotype structure in the human genome

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The structure of haplotype blocks in the human genome

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Drug development for asthma

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Pharmacogenetics in the laboratory and the clinic.

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Pharmacogenetics and future drug development and delivery

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Molecular basis of ethnic differences in drug disposition and response

21 January 2018

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Effect of apolipoprotein E polymorphism and XbaI polymorphism of apolipoprotein B on response to lovastatin treatment in familial and non-familial hypercholesterolaemia.

21 January 2018

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics

21 January 2018

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Prospects and limits of pharmacogenetics: the thiopurine methyl transferase (TPMT) experience

21 January 2018

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21 January 2018

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Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro

21 January 2018

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Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal

21 January 2018

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Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

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11. Gene–nutrient interactions in nutritional epidemiology

21 January 2018

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Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

21 January 2018

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Haplotype tagging for the identification of common disease genes

21 January 2018

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Polymorphisms of the β2-Adrenergic Receptor and Asthma

21 January 2018

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31 March 2020

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Economic and regulatory considerations in pharmacogenomics for drug licensing and healthcare

31 March 2020

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The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG1229

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Dimensions Publication ID

9 August 2017

1047189229

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