(Q35311377)

7 August 2017

title

Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity (English)

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7 August 2017

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N M Gough

1

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7 August 2017

O Bernard

series ordinal

2

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7 August 2017

language of work or name

English

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publication date

1 January 1981

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

volume

78

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7 August 2017

issue

1

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7 August 2017

page(s)

509-513

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Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Nucleotide sequence of immunoglobulin heavy chain joining segments between translocated VH and mu constant regions genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Determination of the primary structure of a mouse IgG2a immunoglobulin. Amino-acid sequence of the H4 cyanogen-bromide fragment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Sequence variation among heavy chains from inulin-binding myeloma proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Immunoglobulin light chain mRNA is processed from large nuclear RNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

A new method for sequencing DNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

The arrangement and rearrangement of antibody genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

A complete immunoglobulin gene is created by somatic recombination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Structural basis for the specificity of antibody–antigen reactions and structural mechanisms for the diversification of antigen-binding specificities

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=319083

Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments

26 September 2018

1 reference

12 December 2020

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1 reference

12 December 2020

Molecular cloning of mouse immunoglobulin heavy chain messenger ribonucleic acids coding for .mu., .alpha., .gamma.1, .gamma.2a, and .gamma.3 chains

1 reference

12 December 2020

Deletions in the constant region locus can account for switches in immunoglobulin heavy chain expression

1 reference

12 December 2020

The joining of V and J gene segments creates antibody diversity

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.78.1.509

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7 August 2017

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7 August 2017

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